2020, Number 2
<< Back Next >>
Rev Cubana Estomatol 2020; 57 (2)
Oral alterations associated to gastroesophageal reflux disease
Otero BY, Llapur ACJ, Osorio NM, Raimundo PE
Language: Spanish
References: 24
Page:
PDF size: 225.48 Kb.
ABSTRACT
Introduction:
Gastroesophageal reflux disease is a functional multifactorial disorder of the upper gastrointestinal tract. Oral alterations are considered to be extraesophageal manifestations of this disease.
Objective:
Determine the oral alterations found in patients with gastroesophageal reflux disease.
Methods:
An observational descriptive study was conducted of 37 patients diagnosed with gastroesophageal reflux disease. The variables analyzed were age, sex, presence of alteration, signs and symptoms, and location. A database was developed with the information recorded, and absolute frequencies and percentages were estimated.
Results:
Of the patients studied, 48.6% had some sort of oral alteration, such as a burning sensation (40.5%) and erythema (35.1%). The regions affected included the soft palate/uvula (72.2%) and the tongue (61.1%).
Conclusions:
Almost half of the patients affected by gastroesophageal reflux had some sort of oral manifestation, the most common of which were a burning sensation, erythema, a dry mouth sensation and ulcerations. The most common locations were the soft palate/uvula and the tongue.
REFERENCES
Olmos JA, Piskorz MM, Vela MF. Revisión sobre enfermedad por reflujo gastroesofágico (ERGE). Acta Gastroenterol Latinoam. 2016 [acceso 19/06/2017];46:160-72. Disponible en: http://www.actagastro.org
Salis G. Revisión sistemática: epidemiología de la enfermedad por reflujo gastroesofágico en Latinoamérica. Acta Gastroenterol Latinoam. 2011 [acceso 19/06/2017];41:60-9. Disponible en: http://www.redalyc.org/articulo.oa?id=199317366013
Savarino E, Bredenoord AJ, Fox M, Pandolfino JE, Roman S, Gyawali CP. Expert consensus document: Advances in the physiological assessment and diagnosis of GERD. Nat Rev Gastroenterol Hepatol. 2017 Sep 27. doi: 10.1038/nrgastro.2017.130.PMID:28951582
Roman S, Gyawali CP, Savarino E, Yadlapati R, Zerbib F, Wu J, et al. Ambulatory reflux monitoring for diagnosis of gastro-esophageal reflux disease: Update of the Porto consensus and recommendations from an international consensus group. Neurogastroenterol Motil. 2017 Oct; 29(10):1-15. doi: 10.1111/nmo.13067. Epub 2017 Mar 31.PMID:28370768
Pandit S, Boktor M, Alexander JS, Becker F, Morris J. Gastroesophageal reflux disease: A clinical overview for primary care physicians.Pathophysiology. 2017 Sep 11;pii: S0928-4680 (17)30039-1. doi: 10.1016/j.pathophys.2017.09.001. PMID:28943113
Shimazu R, Yamamoto M, Minesaki A, Kuratomi Y. Dental and oropharyngeal lesions in rats with chronic acid reflux esophagitis. Auris Nasus Larynx. 2017 Sep 4.pii: S0385-8146(17)30480-7. doi: 10.1016/j.anl.2017.08.011. PMID:28882408
Mantegazza C, Angiero F, Zuccotti GV.Oral manifestations of gastrointestinal diseases in children. Part 3: Ulcerative colitis and gastro-oesophageal reflux disease. Eur J Paediatr Dent. 2016 Sep; 17(3):248-50. PMID: 27759417
Adachi K, Mishiro T, Tanaka S, Yoshikawa H, Kinoshita Y. A Study on the Relationship between Reflux Esophagitis and Periodontitis. Intern Med. 2016;55(18):2523-8. doi: 10.2169/internalmedicine.55.6898. Epub 2016 Sep 15. PMID:27629943
Watanabe M, Nakatani E, Yoshikawa H, Kanno T, Nariai Y, Yoshino A, et al. Oral soft tissue disorders are associated with gastroesophageal reflux disease: retrospective study. BMC Gastroenterol. 2017 Aug 7;17(1):92. doi: 10.1186/s12876-017-0650-5. PMID: 28784097; PMCID: PMC5545853
Khodamoradi Z, Gandomkar A, Poustchi H, Salehi A, Imanieh MH, Etemadi A, et al. Prevalence and Correlates of Gastroesophageal Reflux Disease in Southern Iran: Pars Cohort Study. Middle East J Dig Dis. 2017 Jul;9(3):129-38. doi: 10.15171/mejdd.2017.63. PMID:28894514. PMCID: PMC5585905
Roesch L, Roesch F, Remes JM, Romero G, Mata C, Azamar AA, et al. Dental erosion, an extraesophageal manifestation of gastroesophageal reflux disease. The experience of a center for digestive physiology in Southeastern Mexico. Rev Esp Enferm Dig. 2014 Feb;106(2):92-7. PMID: 24852734
Torres L, Torres N, Vargas G. Dental erosions in patients with gastroesophageal reflux disease in National Hospital ArzobispoLoayza. Rev Gastroenterol Peru. 2012 Oct-Dec;32(4):343-50. PMID: 23307083
Preetha A, Sujatha D, Patil BA, Hegde S. Oral manifestations in gastroesophageal reflux disease. Gen Dent. 2015 May-Jun;63(3):27-31. PMID: 25945775
Vinesh E, Masthan K, Kumar MS, Jeyapriya SM, Babu A, Thinakaran M. A Clinicopathologic Study of Oral Changes in Gastroesophageal Reflux Disease, Gastritis, and Ulcerative Colitis. J Contemp Dent Pract. 2016 Nov 1;17(11):943-7. PMID: 27965506
Di Fede O, Di Liberto C, Occhipinti G, Vigneri S, Lo Russo L, Fedele S, et al. Oral manifestations in patients with gastro-oesophageal reflux disease: a single-center case-control study. J Oral Pathol Med. 2008 Jul;37(6):336-40. doi: 10.1111/j.1600-0714.2008.00646.x. Epub 2008 Feb 15. PMID: 18284539
Marsicano J, de Moura-Grec P, Bonato R, Sales-Peres M de C, Sales-Peres A, Sales-Peres S. Gastroesophageal reflux, dental erosion, and halitosis in epidemiological surveys: a systematic review. Eur J Gastroenterol Hepatol. 2013 Feb;25(2):135-41. doi: 10.1097/MEG.0b013e32835ae8f7. PMID: 23111415
Aframian D, Ofir M, Benoliel R. Comparison of oral mucosal pH values in bulimia nervosa, GERD, BMS patients and healthy population. Oral Dis. 2010 Nov;16(8):807-11. doi: 10.1111/j.1601-0825.2010.01692.x. PMID: 20646236
Sujatha S, Jalihal U, Devi Y, Rakesh N, Chauhan P, Sharma S. Oral pH in gastroesophageal reflux disease. Indian J Gastroenterol. 2016 May;35(3):186-9. doi: 10.1007/s12664-016-0659-7. Epub 2016 May 23. PMID: 27211893
Yoshikawa H, Furuta K, Ueno M, Egawa M, Yoshino A, Kondo S, et al. Oral symptoms including dental erosion in gastroesophageal reflux disease are associated with decreased salivary flow volume and swallowing function. J Gastroenterol. 2012 Apr;47(4):412-20. doi: 10.1007/s00535-011-0515-6. Epub 2011 Dec 27. PMID: 22200941
Farré R. Pathophysiology of gastro-esophageal reflux disease: a role for mucosa integrity? Neurogastroenterol Motil. 2013 Oct; 25(10):783-99. doi: 10.1111/nmo.12201. Epub 2013 Aug 12. PMID:23937353
Linnett V, Seow WK, Connor F, Shepherd R. Oral health of children with gastro-esophageal reflux disease: a controlled study. Aust Dent J. 2002 Jun;47(2):156-62. PMID: 12139271
Alavi G, Alavi A, Saberfiroozi M, Sarbazi A, Motamedi M, Hamedani SH. Dental Erosion in Patients with Gastroesophageal Reflux Disease (GERD) in a Sample of Patients Referred to the Motahari Clinic, Shiraz, Iran. J Dent (Shiraz). 2014 Mar;15(1):33-8. PMID:24738088. PMCID: PMC3986576
De Oliveira P, Paiva S, De Abreu M, Auad S. Dental Erosion in Children with Gastroesophageal Reflux Disease. Pediatr Dent. 2016;38(3):246-50. PMID: 27306250
Petruzzi M, Lucchese A, Campus G, Crincoli V, Lauritano D, Baldoni E. Oral stigmatic lesions of gastroesophageal reflux disease (GERD). Rev Med Chil. 2012 Jul;140(7):915-8. doi: 10.4067/S0034- 98872012000700014. PMID: 23282706