Moreno GJ, Castrejón PAD, Rodríguez EIM

Language: Spanish
References: 14
Page: 205-209
PDF size: 188.66 Kb.

ABSTRACT

Background: calcium hydroxylapatite fillers are being used for treating dark eye bags. In some cases, these injections may result in the formation of pseudo-xanthelasma lesions which are difficult to reverse. Recent studies using Q-switched laser on teeth showed fracture of calcium hydroxylapatite dentine, suggesting the possibility of its use for removal these compounds from the skin.
Objective: to evaluate the clinical response of pseudo-xanthelasma caused by calcium hydroxylapatite fillers to treatment with Q-switched 1 064 nm laser.
Methods: this case series took place from October 2017 to December 2019 in a dermatology outpatient clinic. We evaluated three female patients who were treated with a calcium hydroxylapatite filler for dark eye bags on their lower eye lid, whom one to four weeks after the injection developed white nodules resembling xanthelasma. They received one session of Q-switched 1 064 nm laser and were evaluated six weeks later with a photographic follow-up.
Results: all three patients noted significant clearance of lesions six weeks after treatment with one session of Qswitched 1 064 nm laser, which was noticeable in the photographic follow-up.
Conclusions: Q-switched 1 064 laser is potentially a novel, noninvasive treatment for xanthelasma-like lesions secondary to calcium hydroxylapatite spheres. The possible mechanism may involve fragmentation of calcium hydroxylapatite spheres which accelerates reabsorption as they can be more easily engulfed and removed by macrophages. More studies are needed to define the role of Q-switched laser for treatment of this adverse effect on the skin caused by the deposit of injectable fillers.

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