2021, Number 2
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Dermatología Cosmética, Médica y Quirúrgica 2021; 19 (2)
Secondary Syphilis: The Great Imitator in 2021
Questionnaire
Morales GLC, Guevara SEG
Language: Spanish
References: 26
Page: 183-190
PDF size: 215.70 Kb.
ABSTRACT
Syphilis is an infection caused by the spirochete
Treponema
pallidum that is transmitted by direct contact with a sexual infectious
lesion or by transplacental route during pregnancy. It
has been called the “great imitator” since it has a diversity of
cutaneous manifestations. Secondary syphilis can occur from
the second to eighth week after the initial injury and is characterized
by skin manifestations known as syphilides; however,
affectations can also be found at the oropharynx or systemic
level. Diagnosis is made by non-treponemal and treponemal serological
tests; however, in some patients non-treponemal tests,
mainly VDRL, can be negative, so it is important to consider the
presence of the prozone phenomenon. Benzathine penicillin g
remains the gold standard of treatment for patients with secondary
syphilis, who are not allergic, including patients with HIV.
The educational plan, hygiene measures and sexual education
are fundamental bases to prevent this disease.
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