2021, Number 2
<< Back Next >>
Dermatología Cosmética, Médica y Quirúrgica 2021; 19 (2)
Hyaluronic Acid: Adverse Events and their Treatment. Analysis of 41 Cases in Mexico
Mora S, Espinosa S, Campos G, Gutiérrez R, Labastida O, Nava M, Navarro MA, García P, Ponce F
Language: Spanish
References: 17
Page: 126-131
PDF size: 221.88 Kb.
ABSTRACT
Introduction: the use of hyaluronic acid fillers, approved
since 2004 by the American Society of Plastic Surgeons (asps),
has significantly increased in recent years, becoming one of the
most utilized procedures for facial rejuvenation in Latin America
and Mexico. As with other cosmetic injectable procedures
it is possible that complications or adverse events (AE) occur.
Objective: to identify the possible complications and adverse
events that may develop from the use of these agents, as well
as how are they treated in Mexico.
Methodology: a questionnaire was prepared based on the Diagnosis
and Treatment of Hyaluronic Acid Adverse Event: Latin
American Expert Panel Consensus Recommendations. Seven
dermatologist (dermatological surgeon-oncologist), one plastic
surgeon and one oculoplastic surgeon participated. Therefore,
this group of physicians shared (by answering a questionnaire),
data about patients who developed complications or adverse
events derived from the use of hyaluronic acid fillers, as well as
the treatment they received.
Results: all of the participants reported the occurrence of
complications and adverse events. In this report, we show the
results from the analysis of 41 case reports. Of these, 21 corresponded
to immediate adverse events, 11 were early ae, and
nine corresponded to late ae.
Conclusion: the use of hyaluronic acid fillers is one of the
most frequent facial rejuvenation procedures in Latin America
and it can present adverse events. It is crucially important to
have expert physicians on the field, capable to train other physicians
interested in the use of these products.
REFERENCES
American Society of Plastic Surgeons, Plastic Surgery Statistics Report 2019. Disponible en: https://www.plasticsurgery.org/documents/ News/Statistics/2019/plastic-surgery-statistics-full-report-2019.pdf.
Asz-Sigall D, Íñigo K, Ortega M, Vega M, Arenas R y Tosti A, Alopecia secondary to hyaluronic acid embolization: trichoscopic findings, Skin Appendage Disord 2019; 5(6):396-400.
Jiménez F, Hernández H y López K, Necrosis facial por aplicación de material de relleno. Un caso manejado con apósitos y fibroblastos cultivados, Dermatología cmq 2018; 16(3):222-6.
Aguilar A, García P, Rebollo N, Segura G y Ruiz J, Revisión de materiales de relleno, Dermatología cmq 2015; 13(1):54-64.
Signorini M, Liew S, Sundaram H, De Boulle K, Goodman G, Monheit G et al., Global aesthetics consensus: avoidance and management of complications from hyaluronic acid fillers, evidence and opinion-based review and consensus recommendations, Plast Reconstr Surg 2016; 137:961-71.
Hernández A y Santana N, Enfermedad autoinmunitaria autoinflamatoria inducida por ácido hialurónico: ¿es acaso posible?, Dermatol Rev Mex 2020; 64(6):775-7.
Alcalá D y Martínez E, Rinomodelación con rellenos inyectables, Dermatología cmq 2017; 15(1):55-8.
Plastic Surgery Statistics Report, asps National Clearinghouse of Plastic Surgery Procedural Statistics, 2019.
Vélez E, Cuenca J, Ramos G y Ramos K, Seguridad en la aplicación de rellenos faciales. Medicina basada en evidencia, Cirugía Plástica 2019; 29(1):67-77.
Almeida A, Banegas R, Boggio R, Bravo B, Braz A, Casabona G et al., Diagnóstico e tratamiento: dos eventos adversos do ácido hialurônico: recomendações de consenso do painel de especialistas da América Latina, Surg Cosmet Dermatol 2017; 9(3):204-13.
Castro M y Muñoz J, Evaluación de ácido hialurónico y coctel enzimático en cicatrices. Estudio multicéntrico, Dermatología cmq 2020; 18(2):84-92.
Heydenrych I, Kapoor K, De Boulle K, Goodman G, Swift A, Kumar M et al., A 10-point plan for avoiding hyaluronic acid dermal filler-related complications during facial aesthethic procedures and algorithms for management, Clin Cosmet Invest Dermatol 2018; 11:603-11.
Alcalá D y Martínez E, Rellenos faciales: efectos adversos, Dermatología cmq 2013; 11(1):1-7.
Kenneth D, Dermal fillers and neurotoxins. En The unfavorable result in plastic surgery, Sttutgart, Thieme Editors, 2018, p. 145.
Goodman G, An interesting reaction to a high and low-molecular weight combination hyaluronic acid, Dermatol Surg 2015; 41(suppl. 4):s164-6.
Turkmani M, De Boulle K y Phillip W, Delayed hypersensitivity reaction to hyaluronic acid dermal filler following influenza-like illness, Clin Cosmet Invest Dermatol 2019; 12:277-83.
Urdiales F, Escoda N, Figueiredo V, Lajo J, Mira M, Moreno A et al., Treatment of soft tissue filler complications: Expert Consensus Recommendations, Aesth Plast Surg 2018; 42: 498-510.