medigraphic.com
Órgano Oficial del Hospital Angeles Health System

2021, Number 2

<< Back Next >>

Acta Med 2021; 19 (2)

Acute kidney injury in COVID-19. Analysis at the Hospital Ángeles Mocel

Prado LPM, Cortés CF, Delgado NM, Fernández MVA, Luna HAM, Mesinas GM, García LFV, Villeda AM?, Ovando MDF

Language: Spanish
References: 20
Page: 236-243
PDF size: 201.68 Kb.


ABSTRACT

Introduction: Acute kidney injury (AKI) is common in COVID-19 patients. Nonetheless, its actual incidence is based in case series and retrospective studies, reporting a wide range of presentations. It has been suggested that AKI is an independent risk factor for mechanical ventilation and death in patients with that viral infection. Material and methods: Observational, descriptive, cross-sectional and retrospective study. The files of interned patients at Hospital Ángeles Mocel between March and July 2020, with a COVID-19 diagnosis, were reviewed. Patients over 18 years old, with a confirmed COVID-19 diagnosis and a complete file were included (n = 83). A descriptive analysis to calculate percentages, means and standard deviation was employed. Results: 36.14% of patients developed AKI, 43.3% were classified as KDIGO 1, 20% as KDIGO 2, 36.6% as KDIGO 3, and 23.3% required kidney replacement therapy. Of the patients under invasive mechanical ventilation, 77.7% developed AKI. Out of the total of patients with AKI, 56.6% died. Conclusions: The incidence of AKI in COVID-19 patients in our population, was similar to that reported in the international literature. AKI was more frequent in patients hospitalized in intensive care units and under invasive mechanical ventilation, in which a higher mortality was observed.


REFERENCES

  1. Chaolin Huang, Yeming Wang, Xingwang Li, Lili Ren, Jianping Zhao, Yi Hu et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020; 395 (10223): 497-506.

  2. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020; 382 (8): 727-733.

  3. Ronco C, Reis T, Husain-Syed F. Management of acute kidney injury in patients with COVID-19. Lancet Respir Med. 2020; 8 (7): P738-742.

  4. Hassanein M, Radhakrishnan Y, Sedor J, Vachharajani T, Vachharajani V, Augustine J et al. COVID-19 and the kidney. Cleveland Clinic Journal of Medicine. 2020; 87 (10): 619-631.

  5. Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Lei Dong L. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020; 97 (5): 829-838.

  6. Gabarre P, Dumas G, Dupont T, Darmon M, Azoulay E, Zafrani L. Acute kidney injury in critically ill patients with COVID-19. Intensive Care Med. 2020; 46 (7): 1339-1348.

  7. Sise ME, Baggett MV, Shepard JAO, Stevens JS, Rhee EP. Case 17-2020: a 68-year-old man with COVID-19 and acute kidney injury. N Engl J Med. 2020; 382 (22): 2147-2156.

  8. Pelayo J, Peterson E, Albano J, Patarroyo-Aponte G, Rangaswami J, Bryan Lo K et al. Clinical characteristics and outcomes of community and hospital acquired acute kidney injury with COVID-19 in a US inner city hospital system. Cardiorenal Med. 2020; 10 (4): 223-231.

  9. Chan L, Chaudhary K, Saha A, Chauhan K, Vaid A, Baweja M et al. Acute kidney injury in hospitalized patients with COVID-19. medRxiv. 2020.

  10. Khwaja A. KDIGO clinical practice guidelines for acute kidney injury. Nephron Clin Pract. 2012; 120 (4): 179-184.

  11. Yih-Ting Chen, Shih-Chieh Shao, Cheng-Kai Hsu, I-Wen Wu, Ming-Jui Hung, Yung-Chang Chen. Incidence of acute kidney injury in COVID-19 infection: a systematic review and meta-analysis. Critical Care. 2020; 24: 346.

  12. Pei G, Zhang Z, Peng J, Liu L, Zhang C, Yu C et al. Renal involvement and early prognosis in patients with COVID-19 pneumonia. J Am Soc Nephrol. 2020; 31 (6): 1157-1165.

  13. Hirsch JS, Ng JH, Ross DW, Sharma P, Shah HH, Barnett RL et al. Acute kidney injury in patients hospitalized with COVID-19. Kidney Int. 2020; 98 (1): 209-218.

  14. Batlle D, Soler MJ, Sparks MA, Hiremath S, South AM, Welling PA et al. Acute kidney injury in COVID-19: emerging evidence of a distinct pathophysiology. J Am Soc Nephrol. 2020; 31 (7): 1380-1383.

  15. Hassanein M, Thomas G, Taliercio J. Management of acute kidney injury in COVID-19. Cleve Clin J Med. 2020.

  16. Ronco C, Reis T. Kidney involvement in COVID-19 and rationale for extracorporeal therapies. Nat Rev Nephrol. 2020; 16: 308-310.

  17. Perico L, Benigni A, Remuzzi G. Should COVID-19 concern nephrologists? why and to what extent? The emerging impasse of angiotensin blockade. Nephron. 2020; 1-9.

  18. Ali H, Daoud A, Mohamed MM, Salim SA, Yessayan L, Baharani J et al. Survival rate?in acute kidney injury superimposed COVID-19 patients: a systematic review and meta-analysis. Renal Fail. 2020; 42 (1): 393-397.

  19. Harrison P. COVID-19 and the kidney: another target to attack. Medscape. 2020.

  20. Lineamiento estandarizado para la vigilancia epidemiológica y por laboratorio de la enfermedad respiratoria viral. Secretaría de Salud del Gobierno de México, Abril 2020.




2020     |     www.medigraphic.com