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Medicina & Laboratorio

2013, Número 09-10

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Medicina & Laboratorio 2013; 19 (09-10)


Síndrome antifosfolípido: generalidades y diagnóstico

Escobar MM

Idioma: Español
Referencias bibliográficas: 74
Paginas: 451-464
Archivo PDF: 927.36 Kb.


RESUMEN

El síndrome antifosfolípido ha sido un tema de investigación continua en diferentes áreas de la medicina. El diagnóstico clínico y de laboratorio se realiza teniendo en cuenta los consensos internacionales de Sapporo (1999) y Sydney (2006), los cuales dan las pautas para identificar y caracterizar el síndrome antifosfolípido. El objetivo primordial de este artículo, es describir los avances científicos en el estudio del síndrome antifosfolípido, los criterios actuales de clasificación, el papel de los anticuerpos anticardiolipina, anti β2 glicoproteína I y el anticoagulante lúpico, así como los mecanismos patogénicos e inmunológicos en los que están involucrados estos anticuerpos. También se describen algunas de las manifestaciones clínicas relacionadas y los procedimientos diagnósticos utilizados actualmente para su identificación.


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