2012, Número 09-10
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Medicina & Laboratorio 2012; 18 (09-10)
Hipotiroidismo adquirido en niños
Toro RM, Restrepo GLM, Balthazar GV, Zuluaga ENA, Campuzano MG
Idioma: Español
Referencias bibliográficas: 66
Paginas: 443-458
Archivo PDF: 502.65 Kb.
RESUMEN
el hipotiroidismo es una de las enfermedades endocrinas más frecuentes, sus manifestaciones
se explican por la producción insuficiente de hormonas tiroideas o por su acción
inadecuada en los órganos blanco. Según la causa, el hipotiroidismo se puede clasificar como
congénito o adquirido, y se puede originar de forma primaria en la glándula tiroidea por defectos
en la síntesis y liberación hormonal, o de forma secundaria por alteraciones centrales en el eje
hipotálamo-hipófisis-tiroides. La etiología y las características clínicas del hipotiroidismo en niños
y adolescentes difieren en parte de las presentadas en los adultos; por ello, es fundamental identificar
las manifestaciones particulares de la disfunción tiroidea durante la edad pediátrica, para
lograr un diagnóstico y tratamiento oportunos, los cuales son esenciales para la prevención de
las múltiples complicaciones, especialmente las secuelas neurológicas devastadoras y el retraso
en el desarrollo. En este artículo se revisarán las principales características del hipotiroidismo
adquirido en niños y adolescentes, planteándose a partir de un enfoque clínico simple y útil para
la práctica médica general.
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