2019, Número 4
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Rev Mex Anest 2019; 42 (4)
Saturación venosa central de oxígeno y presión sanguínea en anestesia espinal de pacientes con preeclampsia severa
Gaona‑Ramírez MI, Vázquez‑Rodríguez JG, Lagunes‑Gaona E
Idioma: Español
Referencias bibliográficas: 41
Paginas: 260-267
Archivo PDF: 318.60 Kb.
RESUMEN
Introducción: La monitorización durante la anestesia es obligatoria.
Objetivo: Determinar la saturación venosa central de oxígeno durante anestesia.
Material y métodos: Estudio prospectivo de 25 pacientes con preeclampsia severa sometidas a cesárea bajo anestesia espinal. Se determinó saturación venosa central de oxígeno y presión arterial media: basal, al minuto 12 de la administración de dosis espinal, y al final de la anestesia. Prueba t de Student, coeficiente de correlación de Spearman, p ‹ 0.05 significativa.
Resultados: Saturación venosa central de oxígeno basal, 77.6 ± 7.0%, al minuto 12, 77.9 ± 5.3% y al final de la anestesia, 76.1 ± 7.2%. La saturación venosa central de oxígeno ‹ 70% se presentó en 8% casos (basal) y 20% (final). La presión arterial media basal fue 114.1 ± 13.9 mmHg; al minuto 12, 95.5 ± 15.4 mmHg y al final fue 96.1 ± 11.1 mmHg (p ‹ 0.05). No hubo correlación entre presión arterial media y saturación venosa central de oxígeno. Hubo asociación lineal significativa entre hemoglobina y saturación venosa central de oxígeno.
Conclusión: La saturación venosa central de oxígeno durante anestesia espinal no presentó diferencias significativas. La identificación de pacientes preeclámpticas severas con saturación venosa central de oxígeno ‹ 70% debería alertar a los clínicos sobre un compromiso de la oxigenación tisular. La no correlación entre saturación venosa central de oxígeno y presión arterial media sugiere que los dos parámetros deberían ser medidos e interpretados en forma independiente.
REFERENCIAS (EN ESTE ARTÍCULO)
Sibai B, Dekker G, Kupferminc M. Preeclampsia. Lancet. 2005;365:785-798.
Turner JA. Diagnosis and management of pre-eclampsia: an update. Int J Womens Health. 2010;2:327-337.
Sharwood-Smith G, Clark V, Watson E. Regional anaesthesia for cesarean section in severe preeclampsia: spinal anaesthesia is the preferred choice. Int J Obstet Anesth. 1999;8:85-89.
Visalyaputra S, Rodanant O, Somboonviboon W, Tantivitayatan K, Thienthong S, Saengchote W. Spinal versus epidural anesthesia for cesarean delivery in severe preeclampsia: a prospective randomized, multicenter study. Anesth Analg. 2005;101:862-868.
Henke VG, Leffert LR. Spinal Anesthesia in Severe Preeclampsia. Anesth Analg. 2013;117:686-693.
Chumpathong S, Sirithanetbhol S, Salakij B, Visalyaputra S, Parakkamodom S, Wataganara T. Maternal and neonatal outcomes in women with severe pre-eclampsia undergoing cesarean section: a 10-year retrospective study from a single tertiary care center: anesthetic point of view. J Matern Neonatal Med. 2016;29:4096-4100.
Ginosar Y, Mirikatani E, Drover DR, Cohen SE, Riley ET. ED50 y ED95 of intrathecal hyperbaric bupivacaine coadministered with opioids for cesarean delivery. Anesthesiology 2004;100:676-682.
Dyer RA, Joubert I. A low-dose spinal anaesthesia for caesarean section. Curr Opin Anaesthesiol. 2004;17:301-308.
Van de Velde M, Van Schoubroeck D, Jani J, et al. Combined spinal-epidural anesthesia for cesarean delivery: dose-dependent effects of hyperbaric bupivacaine on maternal hemodynamics. Anesth Analg. 2006;103:187-189.
Assali NS, Prystowski H. Studies on autonomic blockade. 1. Comparison between the effects of tetraethylammonium chloride (TEAC) and high selective spinal anesthesia on blood pressure of normal and toxemic pregnancy. J Clin Invest. 1950;29:1354-1366.
Aya AG, Mangin R, Vialles N, Ferrer JM, Robert C, Ripart J, et.al. Patients with severe preeclampsia experience less hypotension during spinal anesthesia for elective cesarean delivery than healthy parturients: a prospective cohort comparison. Anesth Analg. 2003;97:867-872.
Aya AGM, Vialles N, Tanoubi I, Mangin R, Ferrer JM, Robert C, et al. Spinal anesthesia-induced hypotension: A risk comparison between patients with severe preeclampsia and healthy women undergoing preterm cesarean delivery. Anesth Analg. 2005;101:869-875.
Sharwood-Smith G, Drummond G. Hypotension in obstetric spinal anaesthesia: a lesson from pre-eclampsia. Br J Anaesth. 2009;102:29-24.
Mitterschiffthaler G, Berger J, Habeler R. Spinal anesthesia for cesarean section in preeclamptic parturients. Br J Anaesth. 2002;89. doi 10.1093/bja/89s10023a.
Clark VA, Sharwood-Smith GH, Stewart AVG. Ephedrine requirements are reduced during spinal anesthesia for cesarean section in preeclampsia. Int J Obstet Anesth. 2005;14:9-13.
Chooi C, Cox JJ, Lumb RS, Middleton P, Chemali M, Emmett RS, et al. Techniques for preventing hypotension during spinal anaesthesia for caesarean section. Cochrane Database Syst Rev. 2017;8:CD002251. doi: 10.1002/14651858.CD002251.pub3.
Nebout S, Pirracchio R. Should we monitor ScVO2 in critically ill patients? Cardiol Res Pract. 2012;Article ID 370697:7. http://dx.doi.org/10.1155/2012/370697.
Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med. 2001;345:1368-1377.
Karanam VL, Page NM, Anim-Nyame N. Hypoxia in pre-eclampsia: cause or effect? Curr Women’s Health Rev. 2010;6:1-6. doi: 10.2174157340410793362131.
Kambam JR, Handte RE, Brown WU, Smith BE. Effect of normal and preeclamptic pregnancies on the oxyhemoglobin dissociation curve. Anesthesiology. 1986;65:426-427.
Belfort MA, Anthony J, Saade GR, Wasserstrum N, Johanson R, Clark S, et al. The oxygen consumption/oxygen delivery curve in severe preeclampsia: Evidence for a fixed oxygen extraction state. Am J Obstet Gynecol. 1993;169:1448-1455.
Walley KR. Use of central venous oxygen saturation to guide therapy. Am J Respir Crit Care Med. 2011;184:514-520. doi: 10.1164/RCCM.201010-1584CI.
Berridge J. Influence of cardiac output on the correlation between mixed venous and central venous oxygen saturation. Br J Anaesth. 1992;69:409-410.
Joshi R, De Witt B, Mosier JM. Optimizing oxygen delivery in the critically ill: The utility of lactate and central venous oxygen saturation (ScvO2) as a roadmap of resuscitation in shock. J Emerg Med. 2014;47:493-500. doi: 10.1016/j.emermed.2014.06.016.
Huh JW, Oh BJ, Lim CM, Hong SB, Koh Y Comparison of clinical outcomes between intermittent and continuos monitoring of central venous oxygen saturation (ScvO2) in patients with severe sepsis and septic shock: a pilot study. Emerg Med J. 2013;11:906-909.
Wittayachamnankul B, Chentanakij B, Sruamsiri K, Chattipakorn N. The role of central venous oxygen saturation, blood lactate, and central venous-to-arterial carbon dioxide partial pressure difference as a goal and prognosis of sepsis treatment. J Crit Care. 2016;36:223-229.
American College of Obstetricians and Gynecologist; Task Force on Hypertension in Pregnancy. Hypertension in Pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in pregnancy. Obstet Gynecol. 2013;122:1122-1131. doi: 10.1097/01.AOG.0000437382.03963.
Secretaría de Salud de México. Guía de Práctica Clínica. GPC. Prevención, Diagnóstico, y Tratamiento de la Preeclampsia en segundo y tercer nivel de atención. Evidencias y recomendaciones. México. 16/03/2017.
Prevención, diagnóstico y tratamiento de la Preeclampsia en segundo y tercer nivel de atención. Instituto Mexicano del Seguro Social; Ciudad de México, 16/03/2017.
Norma Oficial Mexicana NOM-006-SSA3-2011, Para la práctica de la anestesiología. SEGOB Secretaría de Gobernación de México Diario oficial de la Federación 23/03/2012. Disponible: https://dof.gob.mx/nota_detalle.php?codigo=5240668&fecha=23/03/2012.
Meyer NJ, Schmith GA. Acute lung injury in pregnancy. In: Bourjeily G, Rosne-Montella K (editors). Pulmonary problems in pregnancy. Rhode Island: Humana Press-Springer Science and Business Media. 2009:355-384.
Simmons LV, Stephenson-Famy A, Easterling T. Optimization of oxygen delivery in a Jehovah’s Witness with anaemia after postpartum haemorrhage. Obstet Med. 2012;5:39-41
Langesæter E, Gibbs M, Dyer R. The role of cardiac output monitoring in obstetric anesthesia. Curr Opin Anaesthesiol. 2015;28:247-253.
Dyer RA, Piercy JL, Reed AR, Lombard CJ, Schoeman LK, James MF. Hemodynamic changes associated with spinal anesthesia for cesarean delivery in severe preeclampsia. Anesthesiology. 2008;108:802-811.
Dyer RA, Piercy JL, Reed AR, Stratihie GW, Lombard CJ, Anthony JA, et al. Comparison between pulse waveform analysis and thermodilution cardiac output determination in patients with severe pre-eclampsia. Br J Anaesth. 2011;106:77-81. doi:10.1093/bja/aeq292.
Karinen J, Rasanen J, Alahuhta S, Jouppila P. Maternal and uteroplacental haemodynamic state in pre-eclamptic patients during spinal anesthesia for cesarean section. Br J Anaesth. 1996;76:16-20.
Nikooseresht M, Seif Rabiei MA, Hajian P, Dastaran R, Alipour N. Comparing the hemodynamics effects of spinal anesthesia in preeclamptic and healthy parturients during cesarean section. Anesth Pain Med. 2016;6:e11519. doi: 10.5812/aapm.11519. eCollection 2016.
Schobel HP, Fischer T, Heuszer K et.al. Preeclampsia: a state of sympathetic hyperactivity. N Engl J Med. 1996;335:1480-1485.
Ashworth JR, Warren AY, Baker PN, Johnson IR. Loss of endothelium-dependent relaxation in myometrial resistance arteries in pre-eclampsia. Br J Obstet Gynaecol. 1997;104:1152-1158.
Bosio PM, Wheeler T, Anthony F et.al. Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance. Am J Obstet Gynecol. 2001;184:146-152.
Visser W, Wallenburg HC. Central hemodynamic observations in untreated preeclamptic patients. Hypertension. 1991;17:1072-1077.