medigraphic.com
Órgano oficial de la Sociedad Mexicana de Cirugía Dermatológica y Oncológica, AC

2019, Número 2

<< Anterior Siguiente >>

Dermatología Cosmética, Médica y Quirúrgica 2019; 17 (2)


Hiperpigmentación mucocutánea inducida por hidroxicloroquina en un paciente con lupus eritematoso sistémico

Medina ALG, Pérez RDO, Ramos RG, López VF

Idioma: Español
Referencias bibliográficas: 29
Paginas: 111-114
Archivo PDF: 166.11 Kb.


RESUMEN

La hiperpigmentación por cloroquina es un efecto adverso bien conocido por el consumo de este fármaco, la cual se presenta algunos meses después de iniciar el tratamiento y afecta la piel y las mucosas. Sin embargo, este efecto adverso se ha descrito con menos frecuencia en pacientes a los que se les prescribe hidroxicloroquina, aunque son pocos los casos reportados en la literatura. En este estudio presentamos el caso de una mujer de 58 años con lupus eritematoso sistémico en tratamiento con hidroxicloroquina, a quien se diagnosticó con hiperpigmentación mucocutánea.


REFERENCIAS (EN ESTE ARTÍCULO)

  1. Ruiz-Irastorza G, Ramos-Casals M, Brito-Zeron P et al., Clinical efficacy and side effects of antimalarials in systemic lupus erythematosus: a systematic review, Ann Rheum Dis 2010; 69:20-8.

  2. Ochsendorf F, Use of antimalarials in dermatology, J Dtsch Dermatol Ges 2010; 8:829-45.

  3. Tenenbaum L y Tuffanelli D, Antimalarial agents. Chloroquine, hydroxychloroquine, and quinaquine, Arch Dermatol 1980; 116:587-91.

  4. Hendrix J y Greer K, Cutaneous hyperpigmentation caused by systemic drugs, Int J Dermatol 1992; 31:458-66.

  5. Dereure O, Drug-induced skin pigmentation. Epidemiology, diagnosis and treatment, Am J Clin Dermatol 2001; 2:253-62.

  6. Melikoglu MA, Melikoglu M, Gurbuz U et al., Hydroxychloroquine-induced hyperpigmentation: a case report, J Clin Pharm Ther 2008; 33:699-701.

  7. Kasper R, Flueckinger B, Gobbi S et al., Hydroxychloroquine-induced hyperpigmentation, J Dtsch Dermatol Ges 2014; 12(2):158-61.

  8. Jallouli M, Frances C, Piette J et al., Hydroxychloroquine-induced pigmentation in patients with systemic lupus erythematous: a case-control study, jama Dermatol 2013; 149: 935-40.

  9. Skare T, Ribeiro C, Souza F et al., Antimalarial cutaneous side effects: a study in 209 users, Cutan Ocul Toxicol 2011; 30:45-9.

  10. Mir A, Booyd K, Meehan S et al., Hydroxycholoroquine-induced hyperpigmentation, Dermatol Online J 2013; 19(12):20723.

  11. Kalampalikis A, Goetze S y Elsner P, Isolated hyperpigmentation of the oral mucosa due to hydroxychloroquine, J Dtsch Dermatol Ges 2012; 10:921-2.

  12. Veraldi S, Schianchi-Veraldi R y Scarabelli G, Pigmentation of the gums following hydroxychloroquine therapy, Cutis 1992; 49:281-2.

  13. True D, Bryant L, Harris M et al., Clinical images: hydroxychloroquine associated mucocutaneous hyperpigmentation, Arthritis Rheum 2002; 46(6):1698.

  14. Millard T, Kirk A y Ratnavel R, Cutaneous hyperpigmentation during therapy with hydroxychloroquine, Clin Exp Dermatol 2004; 29(1):92-3.

  15. Reynaert S, Setterfield J y Black M, Hydroxychloroquine-induced pigmentation in two patients with systemic lupus erythematosus, J Eur Acad Dermatol Venerol 2006; 20(4):487-8.

  16. Amichai B, Gat A y Grunwald M, Cutaneous hyperpigmentation during therapy with hydroxychloroquine, J Clin Rheumatol 2007; 13:113.

  17. Rood MJ, Vermeer MH y Huizinga TW, Hyperpigmentation of the skin due to hydroxychloroquine, Scand J Rheumatol 2008; 37:158.

  18. Puri PK, Lountzis NI, Tyler W et al., Hydroxychloroquine induced hyperpigmentation: the staining pattern, J Cutan Pathol 2008; 35: 1134-7.

  19. Morrison L, Nordlund J y Heffernan M, Persistent cutaneous hyperpigmentation duo to hydroxychloroquinone one year after therapy discontinuation, Dermatol Online J 2009; 15(12):15.

  20. Kalabalikis D, Patsatsi A, Trakatelli MG et al., Hyperpigmented forearms and nail: a quiz, Acta Derm Venereol 2010; 90:657-9.

  21. Cho E, Kim B, Park E et al., Hydroxychloroquine induced hyperpigmentation, J Dermatol 2012; 39:859-60.

  22. Jallouli M, Leroux G, Halabi-Tawil M et al., Skin pigmentation in a patient with systemic lupus erytematosus, Rev Med Interne 2010; 31(8):566-7.

  23. Lisi P, Assalve D y Hansel K, Phototoxic and photoallergic dermatitis caused by hydroxychloroquine, Contact Dermatitis 2004; 50:255-6.

  24. Lerman M, Karimbux N, Guze K et al., Pigmentation of the hard palate, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2009; 107:8-12.

  25. Savage N, Barber M y Adakins K, Pigmentary changes in rat oral mucosa following antimalarial therapy, J Oral Pathol 1986; 15:468-71.

  26. Lippard V y Kauer G, Pigmentation of the palate and subungual tissues associated with suppressive quinacrine hydrochloride therapy, Am J Trop Med Hyg 1945; 25:469-71.

  27. Kleinegger C, Hammond H y Finkelstein M, Oral mucosal hyperpigmentation secondary to antimalarial drug therapy, Oral Surg Oral Med Oral Pathol Oral Rdiol Endod 2000; 90:189-94.

  28. Mattsson U, Halbritter S, Mörner S et al., Oral pigmentation in the hard palate associated with imatinib mesylate therapy: a report of three cases, Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011; 111: 12-6.

  29. Tracy C, Blakey B, Parker G et al., Hydroxychloroquine-induced hyperpigmentation, J Clin Rheumatol 2013; 19:292.




2020     |     www.medigraphic.com