2019, Número 2
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Gac Med Mex 2019; 155 (2)
Linfoma anaplásico de células T grandes primario cutáneo CD30+. Serie de nueve casos
Ruiz-Arriaga LF, Landgrave-Gómez I, Toussaint-Caire S, Lacy-Niebla RM, Vega-Memije ME
Idioma: Español
Referencias bibliográficas: 37
Paginas: 130-135
Archivo PDF: 665.52 Kb.
RESUMEN
Introducción: El linfoma anaplásico de células T grandes CD30+ es un linfoma primario cutáneo en el cual no hay evidencia
de enfermedad sistémica; para su diagnóstico es necesario el estudio histopatológico.
Objetivo: Presentar los casos diagnosticados
en el Departamento de Dermatología del Hospital General “Dr. Manuel Gea González” con linfomas anaplásicos de
células T grandes primarios cutáneos CD30+ durante un periodo de 24 años.
Método: Estudio retrospectivo en el que realizó
estadística descriptiva. Se recopiló información de sexo, edad, características clínicas, resultados de pruebas complementarias,
tratamientos previos y actuales, reportes de los estudios histopatológicos y de inmunohistoquímica.
Resultados: Entre 29 309
expedientes, se encontraron nueve casos (0.000034 %) con diagnóstico de linfoma anaplásico de células T CD30+. Se hizo
la confirmación del diagnóstico histopatológico e inmunohistoquímico por dos dermatopatólogos certificados. La edad
promedio fue de 61.2 años, hubo predominio del sexo femenino y de lesión papular o nodular y topografía variada como
presentación clínica inicial.
Conclusiones: El pronóstico del linfoma anaplásico de células T grandes CD30+ en la población
estudiada fue dependiente del estadio clínico. El tratamiento en etapas tempranas tiene resultados favorables.
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