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2019, Número 1

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Ann Hepatol 2019; 18 (1)


Metabolomics Discloses a New Non-invasive Method for the Diagnosis and Prognosis of Patients with Alcoholic Hepatitis

Michelena J, Alonso C, Martínez-Arranz I, Altamirano J, Mayo R, Sancho-Bru P, Bataller R, Ginès P, Castro A, Caballería J

Idioma: Ingles.
Referencias bibliográficas: 20
Paginas: 144-154
Archivo PDF: 694.58 Kb.


RESUMEN

Sin resumen.


REFERENCIAS (EN ESTE ARTÍCULO)

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  2. Lucey M, Mathurin P, Morgan T. Alcoholic Hepatitis. N Engl J Med 2009; 360: 2758-2769.

  3. European Association for the Study of the Liver. EASL clinical practice guidelines: management of alcoholic liver disease. J Hepatol 2012; 57: 399-420.

  4. Kulkarni K, Tran T, Medrano M, Yoffe B, Goodgame R. The role of the discriminant factor in the assessment and treatment of alcoholic hepatitis. J Clin Gastroenterol 2004; 38: 453-9.

  5. Maddrey WC, Boitnott JK, Bedine MS, Weber FL, Mezey E, White RI. Corticosteroid therapy of alcoholic hepatitis. Gastroenterology 1978; 75: 193-9.

  6. Dunn W, Jamil LH, Brown LS, Wiesner RH, Kim VR, Menon KV, Malinchoc M, et al. MELD accurately predicts mortality in patients with alcoholic hepatitis. Hepatology 2005; 41: 353-8.

  7. Forrest EH, Evans CD, Stewart S, Phillips M, Oo YH, McAvoy NC, Fisher NC, et al. Analysis of factors predictive of mortality in alcoholic hepatitis and derivation and validation of the Glasgow alcoholic hepatitis score. Gut 2005; 54: 1174-9.

  8. Dominguez M, Rincon D, Abraldes JG, Miquel R, Colmenero J, Bellot P, García-Pagán JC, et al. A new scoring system for prognostic stratification of patients with alcoholic hepatitis. Am J Gastroenterol 2008; 103: 2747-56.

  9. Altamirano J, Miquel R, Katoonizadeh A, Abraldes JG, Duarte- Rojo A, Louvet A, Augustin S, et al. A histologic scoring system for prognosis of patients with alcoholic hepatitis. Gastroenterology 2014; 146: 1231-9.

  10. Soga T, Sugimoto M , Honma M, Mori M, Igarashi K, Kashikura K, Ikeda S, et al. Serum metabolomics reveals gamma-glutamyl dipeptides as biomarkers for discrimination among different forms of liver disease. J Hepatol 2011; 55: 896-905.

  11. Seijo S, Lozano JJ, Alonso C, Reverter E, Miquel R, Abraldes JG, Martínez-Chantar ML, et al. Metabolomics discloses potential biomarkers for the noninvasive diagnosis of idiopathic portal hypertension. Am J Gastroenterol 2013; 108: 926-932.

  12. Barr J, Caballería J, Martínez-Arranz I, Domínguez-Díez A, Alonso C, Muntané J, Pérez-Cormenzana M, et al. Obesity dependent metabolic signatures associated with nonalcoholic fatty liver disease progression. J Proteome Res 2012; 11(4): 2521-32.

  13. Louvet A, Naveau S, Abdelnour M, Ramond MJ, Diaz E, Fartoux L, Dharancy S, et al. The Lille model: a new tool for therapeutic strategy in patients with severe alcoholic hepatitis treated with steroids. Hepatology 2007; 45: 1348-54.

  14. Martinez-Arranz I, Mayo R, Perez-Cormenzana M, Mincholé I, Salazar L, Alonso C, Mato JM. Enhancing metabolomics research through data mining. J Proteomics 2015; 127: 275-88.

  15. Hanouneh IA, Zein NN, Cikach F, Dababneh L, Grove D, Alkhouri N, Lopez R, et al. The breathprints in patients with liver disease identify novel breath biomarkers in alcoholic hepatitis. Clin Gastroenterol Hepatol 2014; 12: 516-23.

  16. Lodhi IJ, Semenkovich CF. Peroxisomes: a nexus for lipid metabolism and cellular signaling. Cell Metab 2014; 19: 380-92.

  17. Jump DB. Fatty acid regulation of hepatic lipid metabolism. Curr Opin Clin Nutr Metab Care 2011; 14: 115-20.

  18. Vance JE. Lipoproteins secreted by cultured rat hepatocytes contain the antioxidant 1-alk-1-enyl-2-acylglycerophosphoethanolamine. Biochim Biophys Acta 1990; 1045: 128-34.

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  20. McPhail MJ, Shawcross DL, Lewis MR, Coltart I, Want EJ, Antoniades CG, Veselkov K, et al. Multivariate metabotyping of plasma predicts survival in patients with decompensated cirrhosis. J Hepatol 2016; 64: 1058-67.




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