2018, Número 6
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salud publica mex 2018; 60 (6)
Prevención y control de neoplasias asociadas a VPH en grupos de alto riesgo de la Ciudad de México: el Estudio Condesa
Lazcano-Ponce E, Salmerón J, González A, Allen-Leigh B, León-Maldonado L, Magis C, Aranda-Flores C, Conde-González C, Portillo-Romero AJ, Yunes-Díaz E, Rivera-Rivera L, Vargas G, Nyitray AG, Giuliano AR
Idioma: Ingles.
Referencias bibliográficas: 55
Paginas: 703-712
Archivo PDF: 444.07 Kb.
RESUMEN
Objetivo. Evaluar la efectividad de una estrategia combinada
de vacunación contra el virus de papiloma humano (VPH)
y tamizaje de VPH de alto riesgo para reducir neoplasias
anogenitales y orofaringeas entre hombres que tienen sexo
con hombres, personas con VIH, personas en situación de
calle, mujeres transgénero, trabajadoras sexuales y víctimas
de violación.
Material y métodos. Este estudio evaluará
la efectividad de una estrategia combinada de vacunación y
tamizaje para reducir la ocurrencia de neoplasias intraepiteliales
cervicales grado 2+ o neoplasias intraepiteliales anales
grado NIA2+ utilizando Kaplan-Meier. Se evaluará tiempo de
resultados positivos para tipos específicos de VPH anogenital
a incidencia de lesiones anogenitales con ese tipo de VPH.
Resultados. Las personas vacunadas contra VPH y con
tamizaje de VPH tendrán menor prevalencia e incidencia de
infecciones por VPH y por ende menor frecuencia de lesiones
anogenitales y orofaringeas relacionadas con VPH.
Conclusiones.
Este estudio generará evidencia científica sobre la
efectividad de una estrategia combinada de vacunación y
tamizaje para reducir la carga de neoplasias asociadas al VPH.
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