2018, Número 4
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Rev Mex Cardiol 2018; 29 (4)
Nefropatía inducida por contraste en pacientes con intervención coronaria percutánea primaria con o sin síndrome metabólico
Santibáñez VM, Arreguín PJF, García HE, Medina GG
Idioma: Ingles.
Referencias bibliográficas: 30
Paginas: 152-158
Archivo PDF: 274.97 Kb.
RESUMEN
La nefropatía inducida por contraste (NIC) se define
como el incremento absoluto de creatinina sérica ≥
0.5 mg/dL o un incremento del 25% de la creatinina
basal, sin otra causa identificada, en un periodo de 48
horas posterior a la exposición al medio de contraste.
Objetivo: Determinar el riesgo de NIC en pacientes con
síndrome coronario agudo (SCA) con y sin síndrome
metabólico (SM) tratados con intervencionismo
coronario percutáneo (ICP).
Material y métodos: Estudio
prospectivo, observacional, longitudinal, comparativo, en
pacientes con SCA admitidos a la Unidad de Cuidados
Coronarios o a la Unidad de Cuidados Intensivos. La
ICP fue realizada con creatinina sérica (Crs) previa ≤
1.2 mg/dL. Las determinaciones de creatinina sérica
se efectuaron 24-48 horas postICP. Para el análisis de
las variables cuantitativas se utilizó la prueba de U de
Mann-Whitney y para variables cualitativas, prueba de
Chi cuadrada (χ
2) con nivel de significancia e intervalos
de confianza del 95% con p = 0.05.
Resultados: 420
pacientes de código infarto fueron estudiados, 323
hombres (76.9%), 97 mujeres (23.1%) con edades de
56 a 70 años. Se dividieron en dos grupos: grupo A 176
(41.9%) con SM, grupo B, 244 (58%) sin SM. Se presentó
NIC en 43 pacientes (10.2%) del grupo A y en 29 (6.9%)
del grupo B. RR: 2.05, IC 95% 1.33-3.15, p = 0.0012.
Conclusiones: El SM es un factor de riesgo (FR) para
desarrollar NIC en pacientes con SCA sometidos a ICP.
Por lo tanto, debe tenerse en cuenta para la detección
temprana y prevención de NIC.
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