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2019, Número 1

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Cir Cir 2019; 87 (1)


Comparación del índice de neutrófilos/linfocitos, la escala de SOFA y la concentración sérica de procalcitonina como indicadores de la gravedad de la apendicitis aguda

Godinez-Vidal AR, Sashida-Méndez H, Cruz-Romero CI, Bandeh-Moghaddam H, Gutiérrez-Banda CA, Gracida-Mancilla NI

Idioma: Español
Referencias bibliográficas: 26
Paginas: 12-17
Archivo PDF: 360.96 Kb.


RESUMEN

Introducción: La apendicitis aguda (AA) es una de las principales causas de abdomen agudo. Un retraso en su diagnóstico y tratamiento elevan la morbimortalidad. Objetivo: Evaluar el índice de neutrófilos/linfocitos (INL), la escala SOFA (Sequential Organ Failure Assessment), la procalcitonina (PCT) y la bilirrubina total (BT), y ver si existe relación como determinantes de la gravedad de la AA. Método: Estudio retrospectivo, observacional, para comparar el INL contra biomarcadores (PCT, BT) y contra escalas de gravedad (APACHE II [Acute Physiology and Chronic Health Evaluation] y SOFA) y quirúrgica (Mannheim). Resultados: 82 casos de enero a mayo de 2017. El 80.8% de los casos con peritonitis generalizada presentaron un INL › 12 (p = 0.002). El 66% de los casos con perforación apendicular presentaban un INL › 12 (p = 0.024). El 70% de los casos graves por BT mostraron un INL › 12 (p = 0.004). El 75% de los casos graves por PCT presentaban un INL › 12 (p = 0.006). El 50% de los casos con SOFA › 6 mostraron un INL › 12 (U de Mann-Whitney, p = 0.023). Conclusión: Existe una relación entre el INL tanto con SOFA, BT y PCT, lo cual indica que un INL › 12 puntos podría estar relacionado con peritonitis generalizada y apendicitis perforada.


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