Paniagua CGL, Monroy PE, Juárez AI, Furuya MAT, Vaca PS, Aguilar EL, Gómez MA, González ASE

Idioma: Español
Referencias bibliográficas: 20
Paginas: 103-110
Archivo PDF: 146.30 Kb.

RESUMEN

El objetivo de este estudio fue comparar la efectividad de antibióticos contra bacterias anaerobias facultativas aisladas de pacientes con los canales radiculares infectados. Los microorganismos se identificaron mediante los sistemas; API-STAPH, API-20E, API 20 NE y API Candida. La concentración mínima inhibitoria (CMI) de penicilina, ampicilina, amoxicilina, ceftazidima, oxitetraciclina, clindamicina, cefotaxima y ampicilina más sulbactam se determinó por el método de macrodilución en placa. Se identificaron un total de 42 microorganismos anaerobios facultativos. El 100% de las bacterias Grampositivas fue resistente a la penicilina (CMI₉₀ =143.85 µg/mL), ampicilina (CMI₉₀ = 58.45 µg/mL) y clindamicina (CMI₉₀ = 225 µg/mL). Todas las bacterias Grampositivas fueron sensibles a cefotaxima (CMI₉₀ = 1.71 µg/mL) y a la ampicilina más sulbactam (CMI₉₀ = 1.62 µg/mL). El 100% de las bacterias Gramnegativas fue resistente a la penicilina (CMI₉₀ = 225 µg/mL), ampicilina (CMI₉₀ = 67.94 µg/mL), amoxicilina (CMI₉₀ = 225 µg/mL), oxitetraciclina (CMI₉₀ = 28.11 µg/mL) y clindamicina (CMI₉₀ = 225 µg/mL), pero sensible a cefotaxima (CMI₉₀ = 1.79 µg/ml) y a la ampicilina más sulbactam (CMI₉₀ = 1.83 µg/mL). Los resultados evidenciaron que la cefotaxima y la ampicilina más sulbactam son una alternativa para el tratamiento de las infecciones radiculares.

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