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TIP Revista Especializada en Ciencias Químico-Biológicas

2005, Número 2

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TIP Rev Esp Cienc Quim Biol 2005; 8 (2)


La respuesta SOS en Escherichia coli

Serment-Guerrero J, Breña-Valle M, Espinosa-Aguirre J

Idioma: Español
Referencias bibliográficas: 46
Paginas: 99-105
Archivo PDF: 435.39 Kb.


RESUMEN

Todos los organismos están expuestos a sufrir el ataque de diversos agentes que pueden alterar la estructura química básica de su material genético, como la luz ultravioleta, metabolitos como las aflatoxinas que producen los hongos, o incluso especies reactivas de oxígeno que se generan como producto de la respiración. Para contrarrestar tal efecto a lo largo de la evolución se han desarrollado y seleccionado diferentes estrategias o mecanismos que le permiten sobreponerse a dichas eventualidades. Dentro de éstas se encuentra la respuesta SOS, durante la cual se incrementa la expresión de un grupo de genes cuya función es la de reparar el daño en el DNA y conferir a la célula más oportunidades de sobreponerse y sobrevivir en condiciones de estrés.


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