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2004, Número 4

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Med Cutan Iber Lat Am 2004; 32 (4)


Reacciones cutáneas a heparinas de bajo peso molecular

Rodríguez-Vázquez M, García-Arpa M, Vera-Iglesias E, Romero-Aguilera G, Cortina CP

Idioma: Español
Referencias bibliográficas: 49
Paginas: 177-183.
Archivo PDF: 332.26 Kb.


RESUMEN

Las heparinas de bajo peso molecular (HBPM) han desplazado en los últimos años a las heparinas no fraccionadas por sus mejores propiedades farmacodinámicas y su mayor seguridad y comodidad en la administración. Se han descrito diversas lesiones cutáneas adversas, entre ellas urticaria, necrosis cutánea, eczema localizado en el punto de inyección o eczema diseminado. Presuponemos que son reacciones adversas frecuentes y que están infravaloradas en la literatura médica. De especial interés es conocer que las HBPM presentan reacciones cruzadas entre ellas y a su vez con la heparina no fraccionada, por lo que siempre se deben realizar pruebas alérgicas para descartar o confirmar polisensibilizaciones. En este artículo se revisa la literatura acerca de las reacciones cutáneas adversas de las HBPM.


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