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ISSN 0016-3813 (Impreso)

2017, Número 2

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Gac Med Mex 2017; 153 (2)


Índice de triglicéridos/lipoproteína de alta densidad unida a colesterol (TG/HDL-C) como criterio de riesgo para síndrome metabólico (SMet) y baja sensibilidad a la insulina en sujetos aparentemente sanos

Baez-Duarte BG, Zamora-Gínez I, González-Duarte R, Torres-Rasgado E, Ruiz-Vivanco G, Pérez-Fuentes R

Idioma: Ingles.
Referencias bibliográficas: 31
Paginas: 152-158
Archivo PDF: 102.35 Kb.


RESUMEN

Propósito: Evaluar si el índice TG/HDL-C puede ser considerado como un criterio de riesgo para SMet y baja SI en sujetos aparentemente sanos. Métodos: Los sujetos participantes fueron caracterizados clínica, antropométrica y bioquímicamente. El índice TG/HDL-C se calculó dividiendo los valores de los TG entre los valores del HDL-C. El SMet se diagnosticó mediante los criterios establecidos por el Tercer Reporte del Panel de Tratamiento para Adultos del Programa Nacional de Educación en Colesterol (ATP-III NCEP) de los EE.UU. La SI se evaluó mediante el índice cuantitativo de evaluación de la SI (QUICKI, Quantitative Insulin Sensitivity Check Index). Resultados: En el estudio participaron 813 sujetos, de los cuales 564 eran mujeres y 249 eran hombres. Se encontró asociación entre el TG/HDL-C alto y la SI (razón de momios [RM]: 4.09; p ‹ 0.01) y con el SMet (RM: 15.29; p ‹ 0.01). Se encontró correlación entre el índice TG/HDL-C y el QUICKI (rho: -0.4989; p ‹ 0.01) y con el SMet (rho: 0.6581; p ‹ 0.01). Conclusión: Los resultados muestran una buena correlación y asociación entre el índice TG/ HDL-C y el SMet y con la SI, sugiriendo a este índice como un criterio de riesgo para SMet y SI baja.


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