2017, Número 2
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Acta Pediatr Mex 2017; 38 (2)
Carga viral para citomegalovirus, en líquido de lavado bronquioalveolar, en población pediátrica
Aristizabal-Bernal BH, Rincón-Caballero OL, Cano-Romero MA
Idioma: Español
Referencias bibliográficas: 41
Paginas: 91-100
Archivo PDF: 529.04 Kb.
RESUMEN
Introducción: las infecciones pulmonares son comunes en los
pacientes inmunocomprometidos. La carga viral de citomegalovirus
se utiliza de rutina para determinar en qué momento se debe iniciar
la terapia preventiva en hospederos inmunocomprometidos, diagnosticar
enfermedad activa y supervisar la repuesta a una terapia
implementada.
Objetivo: describir el valor de la carga viral de citomegalovirus en
líquido de lavado bronquioalveolar
vs. sangre periférica en población
pediátrica con signos de infección respiratoria.
Material y Métodos: estudio descriptivo, observacional de
16 pacientes pediátricos y 19 episodios, a quienes se les realizó, de
manera simultánea, la carga viral de citomegalovirus en sangre y
lavado bronquioalveolar.
Resultados y Conclusiones: todas las cargas virales de citomegalovirus
realizadas en lavado bronquioalveolar fueron positivas
y en general se obtuvieron valores más elevados que en sangre, lo
que sugiere una mayor sensibilidad de la prueba cuando se realiza en
este tipo de muestra, en pacientes con sospecha clínica de infección
respiratoria por citomegalovirus, lo cual la convierte en una ayuda
diagnóstica importante según lo muestran los resultados obtenidos.
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