Solís-Martínez R, Hernández-Flores G, Jiménez-Luevano MÁ, Ortiz- Lazareno PC, Cancino-Marantes M, Cruz-Gálvez CC, Bravo- Cuellar A

Idioma: Español
Referencias bibliográficas: 13
Paginas: 11-15
Archivo PDF: 525.85 Kb.

RESUMEN

La prevalencia de obesidad ha incrementado en todo el mundo en los últimos años. La acumulación de macrófagos en el tejido adiposo juega un papel primordial para predisponer un estado de inflamación subclínica de bajo grado. La polarización de estas células hacia un fenotipo proinflamatorio, estimula la producción y secreción de citocinas y marcadores metabólicos que provocan desregulación del metabolismo, esto favorece la aparición de enfermedades metabólicas como Diabetes Mellitus tipo 2 y ateroesclerosis.

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