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2016, Número 6

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Rev ADM 2016; 73 (6)


Fusobacterium nucleatum ¿Un patógeno periodontal promotor de carcinogénesis colorrectal?

Zerón GVA, Porras LD

Idioma: Español
Referencias bibliográficas: 37
Paginas: 280-285
Archivo PDF: 276.01 Kb.


RESUMEN

El Fusobacterium nucleatum es una bacteria anaerobia Gram negativa, es un residente común en el biofilm oral y se ha encontrado una estrecha asociación entre las fusobacterias y las periodontitis. El Fusobacterium nucleatum se ha asociado con el cáncer colorrectal, pero la causalidad y el mecanismo subyacente aún no se han establecido. La microbiota intestinal humana tiene un papel reconocido en el cáncer colorrectal. Se ha encontrado que el Fn se adhiere, invade, e induce respuestas inflamatorias oncogénicas que estimulan el crecimiento de las células de cáncer colorrectal a través de un factor de la adhesina FadA.


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