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2016, Número 1

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Rev Cubana Hematol Inmunol Hemoter 2016; 32 (1)


Comportamiento de las células asesinas naturales, las dendríticas y los macrófagos, en el embarazo

Sánchez SM, Pino BD, Díaz DG, Macías AC, del Valle PL

Idioma: Español
Referencias bibliográficas: 83
Paginas: 15-29
Archivo PDF: 121.80 Kb.


RESUMEN

La implantación de un embrión semialogénico en el útero materno constituye una paradoja inmunológica y es uno de los fenómenos que abre más interrogantes dentro del campo de la Inmunología. Mientras que en un determinado momento se consideró que la interfase materno-fetal era un sitio inmunológicamente privilegiado, hoy se sabe que ocurre un reconocimiento del feto semialogénico por el sistema inmune de la madre. Sin embargo, a pesar de este reconocimiento inmunológico se han descubierto varios mecanismos que pueden explicar por qué la madre no rechaza al feto antigénicamente diferente. Estos mecanismos incluyen, tanto factores fetales como factores locales maternos, donde están incluidos los elementos de la respuesta inmunitaria adaptativa e innata. En este trabajo se hace referencia a la importante función que desempeñan las células asesinas naturales, las células dendríticas y los macrófagos en el embarazo.


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