2005, Número 2
Siguiente >>
Salud Mental 2005; 28 (2)
Conferencia Magistral. Desarrollo de la genética y la medicina genómica.
Salamanca F
Idioma: Español
Referencias bibliográficas: 82
Paginas: 1-12
Archivo PDF: 121.22 Kb.
FRAGMENTO
Agradezco esta honrosa distinción al Comité Organizador de la Reunión de Investigación, particularmente al doctor Gerardo Heinze, Director del Instituto Nacional de Psiquiatría Ramón de la Fuente, que me permite referirme a los más sobresalientes desarrollos de la Genética Humana en los últimos años, en esta conferencia que honra la memoria del doctor Raúl Hernández Peón, uno de los más ilustres investigadores de la ciencia nacional.
Las aportaciones del doctor Hernández Peón en el campo de la Neurofisiología tuvieron notable repercusión internacional y su destacada actividad docente dejó profunda huella en la medicina nacional y en el ámbito latinoamericano.
No es el momento de referir aquí sus múltiples y señalados logros. Baste mencionar que el emocionado tributo póstumo quedó para la historia, plasmado bajo la pluma eminente del maestro Ramón de la Fuente, en las páginas de la
Gaceta Médica de México (12), órgano oficial de la Academia Nacional de Medicina y publicación médica latinoamericana que durante más años se ha publicado en forma ininterrumpida.
REFERENCIAS (EN ESTE ARTÍCULO)
1. ARBER W: DNA modification and restriction. Prog Nucl Acid Res Mol Biol, 14:1-18, 1974
2. ASSADY S, MAOR G, AMIT M, ITSKOVITZ E, SKORECKI K: Insulin production by human embryonic stem cells. Diabetes, 50:1691-1697, 2001.
3. AVERY OT, MAC LEOD CM, McCARTY M: Studies on the chemical nature of the substance inducing transformation of pneumococcal types. J Exp Med, 98:451-460, 1944.
4. BALL P: Paper trail reveals references go unread by citing authors. Nature, 420:594, 2002.
5. BLUMK, NOBLE E, SHERIDAN P, MONTGOMERY A, RITCHIET: Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA, 263:2055-2060, 1990.
6. CIBELLI JB: The first human cloned embryo. Sci Amer, 286:42-49, 2002.
7. CLEAVER JE: Defective repair replication of DNA in Xeroderma pigmentosum. Nature, 218:652-656, 1968.
8. COLLABORATIVE LINKAGE STUDY OF AUTISM: An autosomal screen for autism. Am J Med Genet (Neuropsychiatric Genetics), 88:609-615, 1999.
9. CRICK F: The double helix: a personal view. Nature, 248:766-769, 1974.
10. CRICK F, KOCH C: A framework for consciousness. Nature Neurosci, 6:119-126, 2003.
11. CRUZ C, CAMARENA B, MEJIA JM, PAEZ F, EROZA V: The dopamine D2 receptor gene taq I A1 polymorphism and alcoholism in a Mexican population. Arch Med Res, 26:421-426, 1995.
12. DE LA FUENTE R: Raúl Hernández Peón. In memoriam. Gac Med Mex, 98:1082-1084, 1968.
13. DONIS-KELLER H: Human Gene Mapping Techniques: A Laboratory Manual. Stockton Press, Nueva York, 1991.
14. EBERHARD G, FRANZENG, LOW B: Schizophrenia susceptibility and A2A antigens. Neuropsycobiol, 1:211-222, 1975.
15. EBSTEIN RP, NOVICK O, UMANSUY R, PRIEL B, OSHER Y: Dopamine D4 receptor (D4DR) exon III polymorphism associated with the human personality trait of novelty seeking. Nature Genet, 12:78-80, 1995.
16. FRANKLIN RE, GOSLIN RG: Molecular configuration in sodium thymonucleate. Nature, 171:740-741, 1953.
17. GOUL DE: Adrenal hormones supress cell division in the adult rat dentate gyrus. J Neurosci, 12:3642-3650, 1992.
18. GRANDY D, LITT M, ALLEN M, BUNZOW J, MARCHIONI M: The human dopamine D2 receptor gene is located on chromosome 11 at q22-23 and identifies a taq I RFLP. Am J Hum Genet, 45:778-785, 1989.
19. GRIFFITH F: The significance of pneumococal types. J Hyg, 27:113-159, 1928.
20. HALES T: Ann Math (Aún en revisión)
21. HAMER HD, HUS, MAGNUSON VL, HUN, PATTATUCHI AML: A linkage between DNA markers on the X chromosome and male sexual orientation. Science, 261:321-327, 1993.
22. HODGKINSON S, MULLAN M, MURRAY RM: The genetics of vulnerability to alcoholism. En: McGuffin P, Murray R (eds.) The New Genetics of Mental Illness. Mental Healthy Foundation, 182:197, Londres, 1991.
23. HOLMES FL: Meselson Stahl and the Replication of DNA: A History of the Most Beatiful Experiment in Biology. Harvard University Press, Boston, 2003.
24. HOLTON G: La Imaginación Científica. Fondo de Cultura Económica, México, 1989.
25. INTERNATIONAL HUMAN GENOME SEQUENCING CONSORTIUM: Finishing the euchromatic sequence of the human genome. Nature, 431:931-945, 2004.
26. JACOB F, MONOD J: Genetic regulatory mechanisms in the synthesis of proteins. J Mol Biol, 3:318-324, 1961.
27. JOHANNSEN WL: Arveligheds Laerens Elementer. Copenhaguen, 1905.
28. JUDSON HF: The Eighth Day of Creation. The Markers of the Revolution in Biology. Simon and Schuster, Nueva York, 1979.
29. KEHAT I: Human embryonic stem cells can differentiate into myocytes with structural and functional properties of cardiomyocytes. J Clin Invest, 108:407-414, 2001.
30. KENDLER KS, GRUENBERG AM, STAUSS JS: An independent analysis of the Copenhagen sample of the Danish adoption study of schizophrenia. Arch Gen Psychiatry, 38:973-993, 1981.
31. KETY SS, ROSENTHAL D, WENGER PH: The type and prevalence of mental illness in the biological and adoptive familie of adopted schizophrenics. En: Rosenthal D, Kety SS (eds.) The Transmission of Schizophernia. Pergamon Press, 89, Oxford, 1968.
32. KING MC, MARKS JH, MANDELL JB: Breast and ovarian cancer risks due to inherited mutations in BRCA1 and BRCA2. Science, 302:643-646, 2003.
33. KONO T, OBATA Y, WUQ, NIWAK, ONO Y: Birth of parthenogenetic mice that can develop to adulthood. Nature, 428:860-864, 2004.
34. KORNACK D, RAKIC P: Continuation of neurogenesis in the hippocampus of the adult macaque monkey. Proc Natl Acad Sci USA, 96:5768-5773, 1999.
35. KUKELOV V: Multipotent stem/progenitor cells with similar properties obtained from two neurogenic regions of adult human brain. Exp Neurol, 156:333-334, 1999.
36. LAI CSG, FISHER SE, HURST JA, YARGA K, HADEM F, MONACO AP: A forkhead-domain gene is mutated in a severe speech and language disorder. Nature, 413:519-523, 2001.
37. LEE SH: Efficient generation of mid brain neurons from mouse embryonic stem cells. Nat Biotechnol, 18:675-679, 2000.
38. LEJEUNE J: Le mongolisme. Premier exemple daberration autosomique humaine. Ann Genet Semaine Hop, 1:41-52, 1959.
39. LENGAUER C, SPEICHER MR, POPPS: Chromosomal bar codes produced by multicolor fluorescence in situ hybridization with multiple YAC clones and whole chromosome painting probes. Hum Mol Genet, 2:505-512, 1993.
40. MARSHALL E: Gene therapy´s growing pains. Science, 269:1050-1055, 1995.
41. MATTSON MP: Pathways towards and away from Alzheimer´s disease. Nature, 430:631-639, 2004.
42. MELO JA, SHENDURE J, POCIASK K, SILVER LM: Identification of sex-specific quantitative trait locus controlling alcohol preference in C57BL/6 mice. Nature Genet, 13:147-153, 1996.
43. MESELSON M, STAHL FW: The replication of DNA in Escherichia coli. Proc Natl Acad Sci USA, 44:671-682, 1958.
44. MORGAN TH: Sex limited inheritance in Drosophila. Science, 32:120-122, 1910.
45. MULLIS KB: Specific synthesis of DNA in vitro via a polymerase-catalyzed chain reaction. Methods Enzymol, 155:335-350, 1987.
46. MURRAY A, SZOSTAK JW: Construction of artificial chromosomes in yeast. Nature, 305:189-193, 1983.
47. MURRAY M, FISHER I: Transplantation and gene therapy. Combined approaches for repair of spinal cord injury. Neuroscientist, 7:28-41, 2001.
48. NATHANS D, SMITH HO: Restriction endonucleases in the analysis and restructuring of DNA molecules. Ann Rer Biochem, 44:273-287, 1975.
49. NATURE (Suplemento especial): The double helix. 50 years. 421:395-453, 2003.
50. NIRENBERG W, MATTHAEI JH: The dependence of cell-free protein synthesis in E. coli upon naturally occurring or synthetic polynucleotides. Proc Natl Acad Sci USA, 47:1558-1602, 1961.
51. OLBY R: Quiet debut for the double helix. Nature, 421:402-405, 2003.
52. PAULING L: The Nature of Chemical Bond. Cornell University Press, Nueva York, 1960.
53. PAULING L, IMO HA, SINGER SJ, WELLS IC: Sickle cell anemia, a molecular disease. Science, 110:543-546, 1949.
54. PLOMIN R, DEFRIES JC, McCLEARN GE, McGUFFIN P: Behavioral Genetics. Worth Publishers, Nueva York, 2001.
55. RIDEOUT WM, HOCHEDLINGER K, KYBA M, DALEY GQ, JAENISCH R: Correction of a genetic deffect by nuclear transplantation and combined cell and gene therapy. Cell, 109:17-27, 2002.
56. ROY NS: In vitro neurogenesis by progenitor cells isolated from the adult human hypocampus. Nature Med, 6:271-277, 2000.
57. SALAMANCA F: Gregor Mendel. El Olvidado Monje del Huerto. CONACYT, México, 1986.
58. SALAMANCA F: Citogenética Humana. Fundamentos y Aplicaciones Clínicas. Editorial Médica Latinoamericana, México, 1990.
59. SALAMANCA F: Keeping Mendel in mind. Nature, 412:118, 2001.
60. SALAMANCA F: Nature, 25 de abril de 1953. Gac Med Mex, 140:246-250, 2004.
61. SALAMANCA F: La aplicación clínica de las células troncales (transplante nuclear). En: Cano-Valle F (ed.) Clonación en Humanos. UNAM, 73-86, México, 2003.
62. SALAMANCA-BUENTELLO F, PERSAD DD, COURT E, MARTIN D, DAAR A, SINGER P: Nanotechnology and the Developing Words. PLOS MEDICINE, 2005 (En prensa).
63. SALAMANCA-BUENTELLO F, SALAMANCA-GOMEZ F: Clinical research, genomic medicine, and scientific evaluation. BMJ, 2005 (En prensa).
64. SARAMAGO J: El Hombre Duplicado. Alfaguara, México, 2003.
65. SHIZOPHRENIA COLLABORATIVE LINKAGE GROUP (Chromosome 22): A combined analysis of D22S278 marker alleles in affected sib-pairs: support for a susceptibility focus for schizophrenia at chromosome 22q12. Am J Med Genet, 67:40-45, 1996.
66. SCHRODINGER E: What is Life? Cambridge University Press, Nueva York, 1944.
67. SCIENCE: Genes and Behaviour. 267:1637-1816, 1994.
68. SHAMBLOT MJ: Derivation of pluripotent stem cells from cultured human primordial germ calls. Proc Nat Acad Sci USA, 95:13726-13731, 1998.
69. SHERWOOD P: DNA from Alberts to Zinder. Nature, 422:806-807, 2003.
70. STRASSER BJ: Who cares about the double helix? Nature, 422:803-804, 2003.
71. SUTTON WS: The chromosomes in heredity. Biol Bull, 4:231-251, 1903.
72. THE HUNTINGTON´S DISEASE COLLABORATIVE RESEARCH GROUP: A novel gene containing a trinnucleotide repeat that is expanded and uns table on Huntington disease chromosome. Cell, 72:971-983, 1993.
73. TJIO JH, LEVAN A: The chromosome number of man. Hereditas, 42:1-6, 1956.
74. VAN PRAAG H: Running increases cell proliferation and neurogenesis in the adult mouse dentate gyrus. Nature Neuroscis, 266-270, 1999.
75. VOGELSTAIN B, ALBERTS B, SHINE K: Please dont call it cloning! Science, 295:1237, 2002.
76. WATSON JD: The Double Helix: A Personal Account of the Discovery of the Structure of DNA. Atheneum, Nueva York, 1968.
77. WATSON JD: DNA. The Secret of Life. William Heinemann, Londres, 2003.
78. WATSON JD, CRICK FHC: Molecular structure of nucleic acids. Nature, 171:737-738, 1953.
79. WATT FM, HEGAN BLM: Out of Eden: stem cells and their niches. Science, 287:1427-1430, 2000.
80. WILKINS MU, STOKES AR, WILSON HR: Molecular structure of deoxy pentose nucleic acids. Nature, 171:738-740, 1953.
81. WILLIAMS NM, REES MI, HOLMANS P, NORTON N, CARDNO AG: A two stage genoma scan of schizophrenia susceptibility genes in 196 affected siblings pairs. Hum Mol Genet, 8:1729-1740, 1999.
82. ZHANG SC: In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol, 19:1129-1133, 2001.