2005, Número 4
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salud publica mex 2005; 47 (4)
Trastornos de la conducta alimentaria como factor de riesgo para osteoporosis
Rivera-Gallardo MT, Parra-Cabrera MS, Barriguete-Meléndez JA
Idioma: Español
Referencias bibliográficas: 120
Paginas: 308-318
Archivo PDF: 146.69 Kb.
RESUMEN
Los trastornos de la conducta alimentaria son comunes en
mujeres jóvenes con una prevalencia estimada de entre
4-5%. La pérdida de masa ósea es una complicación física de
la anorexia nervosa y trastorno alimentario no especificado
que afecta tanto a hueso cortical como trabecular. El
efecto sinérgico de la desnutrición y la deficiencia de estrógenos
produce una pérdida de masa ósea a través del
desacoplamiento entre resorción osteoclástica y formación
osteoblástica. La severidad varía dependiendo de la duración
de la enfermedad, el peso menor alcanzado y la actividad
física. La repercusión a largo plazo es evidente pues
existe un incremento en el riesgo de fractura en las pacientes
que han padecido anorexia nervosa. La primera línea de
tratamiento para recuperar la masa ósea es la rehabilitación
nutricia y un incremento de peso. La terapia de reemplazo
hormonal podría ser efectiva si se combina con
métodos anabólicos. Los términos osteopenia y osteoporosis
fueron adoptados para definir la deficiencia de masa
ósea en adultos. Los autores de las publicaciones que fueron
revisadas utilizaron dichos términos para definir datos
densitométricos en sujetos jóvenes que no han alcanzado
la masa ósea pico. Sugerimos el término “hipo-osteogenesia”
para definir el desarrollo deficiente de masa ósea en
adolescentes o niños.
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