2016, Número S1
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Rev Mex Anest 2016; 39 (S1)
Nuevos usos de la vieja amiga: ketamina
Chenge-Said J, Campeñacho-Asencio MÁ, Castellanos-Acuña MJ
Idioma: Español
Referencias bibliográficas: 20
Paginas: 262-264
Archivo PDF: 156.96 Kb.
FRAGMENTO
En 1950 las industrias Parke Davis en su búsqueda por encontrar el anestésico ideal que no causara depresión respiratoria ni cardiovascular y que además produjera analgesia sintetizan dos fármacos, la CI-395 (fenciclidina) y la CI-400 (clorhidrato de N-etil-fenilcicloxamina). Estos fármacos cumplían con los objetivos buscados pero tenían un gran defecto, causaban severos efectos psicodislépticos caracterizados por sueños «vividos» y alucinaciones. A pesar de lo anterior la fenciclidina se comercializó en Estados Unidos bajo el nombre de Sernyl
® y debido al uso recreacional excesivo (rápidamente se dio a conocer como «polvo de ángel») se detuvo su producción en 1978.
REFERENCIAS (EN ESTE ARTÍCULO)
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