2005, Número 3
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Rev Invest Clin 2005; 57 (3)
La prolactina en el sistema inmunológico: aspectos de síntesis y efectos biológicos
Méndez I, Cariño C, Díaz L
Idioma: Español
Referencias bibliográficas: 79
Paginas: 447-456
Archivo PDF: 133.83 Kb.
RESUMEN
La prolactina es una hormona que fue considerada durante mucho tiempo de origen exclusivamente hipofisario, y cuya función más importante era la promoción de la lactancia. Sin embargo, la prolactina no sólo se sintetiza en diversos sitios del organismo, sino que también participa en una amplia variedad de procesos biológicos. Dentro de los sitios de síntesis extrahipofisarios de esta hormona se encuentran diversas células del sistema inmunológico. A este nivel, la prolactina actúa afectando desde la proliferación celular hasta el estado inmune del individuo. En esta revisión presentamos algunos aspectos relativos a la prolactina de origen linfocitario tales como su síntesis, su participación en el sistema inmunológico y su relación con estados de autoinmunidad.
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