2015, Número S2
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Rev Med Inst Mex Seguro Soc 2015; 53 (S2)
Prevalencia de genotipos de VPH en México y en el mundo detectados mediante Linear Array
Flores-Miramontes MG, Torres-Reyes LA, Aguilar-Lemarroy A, Vallejo-Ruíz V, Piña-Sánchez P, Cortés-Gutiérrez E, Reyes-Leyva J, Jave-Suárez LF
Idioma: Español
Referencias bibliográficas: 35
Paginas: 122-130
Archivo PDF: 410.01 Kb.
RESUMEN
La infección por el virus de papiloma humano (VPH) es
el principal factor asociado al desarrollo de cáncer cervicouterino
(CaCU). Conocer la prevalencia de los diversos
VPH en distintas etapas del desarrollo del CaCU es
relevante para determinar los VPH de riesgo oncogénico,
establecer el desarrollo de estrategias de tamizaje
y la evaluación de programas de prevención, así como
para el diseño de vacunas. El presente trabajo es un
metaanálisis sobre prevalencia de VPH a nivel mundial
y en México de estudios que hayan utilizado el Linear
Array
® HPV Genotyping Test como prueba diagnóstica
(prueba comercial que a la fecha identifica la mayor
cantidad de genotipos de VPH en una sola muestra), en
ADN de raspados cervicales de mujeres con diagnóstico
citológico normal, con lesión intraepitelial escamosa
de bajo grado (LIEBG), con lesión intraepitelial escamosa
de alto grado (LIEAG) y con CaCU. En mujeres
con este tipo de cáncer, los genotipos más prevalentes
después de los VPH-16 y -18 varían dependiendo de la
región geográfica, lo que soporta la necesidad de desarrollar
estrategias de detección y prevención acordes a
las características de la población.
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