2015, Número 4
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Acta Med 2015; 13 (4)
Cannabinoides: utilidad actual en la práctica clínica
Serra RSV, Palomares VPR, Pinto SMEAlmeida GE
Idioma: Español
Referencias bibliográficas: 57
Paginas: 244-250
Archivo PDF: 149.83 Kb.
RESUMEN
El avance de las ciencias médicas en el último siglo ha sido a pasos agigantados. Cada día contamos con más recursos farmacológicos para curar y controlar distintas patologías, y paliar su sintomatología con mayor eficacia y seguridad para el paciente. Dentro de este gran arsenal farmacológico, existe un grupo aún entre sombras que parece prometedor para el manejo del dolor y algunos otros síntomas asociados a patologías específicas: los cannabinoides. Existen miedos y tabús alrededor de los cannabinoides debido a la reputación de la planta
Cannabis sativa, conocida comúnmente como “marihuana”, como droga recreativa. A pesar de esto, entre sus aproximadamente 70 cannabinoides endógenos o fitocannabinoides, se encuentran algunos que resultan útiles en la práctica clínica al actuar de manera selectiva en receptores del sistema endocannabinoide humano, brindando alivio tanto al dolor como a otros síntomas refractarios al tratamiento convencional. Aún hay necesidad de estudios adicionales para demostrar la eficacia de este grupo farmacológico; sin embargo, los ensayos clínicos que existen hasta el momento parecen prometedores en su potencial terapéutico.
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