Cabrera OM, Benítez RDB

Idioma: Español
Referencias bibliográficas: 48
Paginas: 217-226
Archivo PDF: 471.01 Kb.

RESUMEN

La estimulación cardíaca permanente se indica en pediatría, con mayor frecuencia, debido al bloqueo aurículo-ventricular. El ventrículo derecho ha sido tradicionalmente el sitio estimulado, dada la factibilidad del acceso, la estabilidad del electrodo y el mantenimiento de umbrales crónicos adecuados. Sin embargo, dicha estimulación se asocia a un patrón disincrónico de activación ventricular, que puede producir remodelado y deterioro de la función ventricular izquierda. En la población pediátrica, donde la estimulación se inicia muchas veces desde edades tempranas y con una larga expectativa de vida, constituye una premisa la preservación de la función cardíaca, por lo que la prevención de la disincronía mediante la utilización de sitios alternativos de estimulación, más que una prioridad, constituye un reto. El presente artí- culo tiene el objetivo de mostrar los efectos de la estimulación ventricular derecha, así como las evidencias demostradas del beneficio e implicaciones clínicas y prácticas de los sitios alternativos de estimulación en la población pediátrica.

REFERENCIAS (EN ESTE ARTÍCULO)

1. van Geldorp IE, Vanagt WY, Prinzen FW, Delhass T. Chronic ventricular pacing in children: toward pre-vention of pacing-induced heart disease. Heart Fail Rev. 2011;16:305-14.

2. Vatasescu R, Shalganov T, Paprika D, Kornyei L, Pro-dan Z, Bodor G, et al. Evolution of left ventricular function in paediatric patients with permanent right ventricular pacing for isolated congenital heart block: a medium term follow-up. Europace. 2007;9(4):228-32.

3. Shalganov TN, Paprika D, Vatasescu R, Kardos A, Mihalcz A, Kornyei L, et al. Mid-term echocardio-graphic follow up of left ventricular function with permanent right ventricular pacing in pediatric patients with and without structural heart disease. Cardiovasc Ultrasound. 2007;5:13-7.

4. Moak JP, Barron KS, Hougen TJ, Wiles HB, Balaji S, Sreeram N, et al. Congenital heart block: develop-ment of late-onset cardiomyopathy, a previously underappreciated sequela. J Am Coll Cardiol. 2001; 37:238-42.

5. Tantengco MV, Thomas RL, Karpawich PP. Left ven-tricular dysfunction after long-term right ventricu-lar apical pacing in the young. J Am Coll Cardiol. 2001;37:2093-100.

6. Karpawich PP, Mital S. Comparative left ventricular function following atrial, septal, and apical single chamber heart pacing in the young. Pacing Clin Electrophysiol. 1997;20:1983-8.

7. Gebauer RA, Tomek V, Salameh A, Marek J, Chalou-pecký V, Gebauer R, et al. Predictors of left ventric-ular remodelling and failure in right ventricular pacing in the young. Eur Heart J. 2009;30:1097-104.

8. Kim JJ, Friedman RA, Eidem BW, Cannon BC, Arora G, Smith O, et al. Ventricular function and long-term pacing in children with congenital complete atrioventricular block. J Cardiovasc Electrophysiol. 2007;18:373-7.

9. Vanagt WY, Prinzen FW, Delhaas T. Physiology of cardiac pacing in children: the importance of the ventricular pacing site. Pacing Clin Electrophysiol. 2008;31:S24-7.

10. 10.Chiesa P, Cuesta A, Dutra S, Matto S, Morales J, Giudice J, et al. Miocardiopatía dilatada en la edad pediátrica por marcapasos con estimulación en el ápex del ventrículo derecho. Arch Pediatr Urug. 2008;79:125-38.

11. 11.Sweeney MO, Prinzen FW. A new paradigm for phy-siologic ventricular pacing. J Am Coll Cardiol. 2006; 47:282-8.

12. 12.Sweeney MO, Prinzen FW. Ventricular pump func-tion and pacing: physiological and clinical integra-tion. Cir Arrhythm Electrophysiol. 2008;1:127-39.

13. 13.Baller D, Wolpers HG, Zipfel J, Bretschneider HJ, Hellige G. Comparison of the effects of right atrial, right ventricular apex and atrioventricular sequen-tial pacing on myocardial oxygen consumption and cardiac efficiency: a laboratory investigation. Pacing Clin Electrophysiol. 1988;11:394-403.

14. 14.Karpawich PP, Rabah R, Haas JE. Altered cardiac histology following apical right ventricular pacing in patients with congenital atrioventricular block. Pa-cing Clin Electrophysiol. 1999;22:1372-7.

15. 15.Spragg DD, Leclercq C, Loghmani M, Faris OP, Tunin RS, DiSilvestre D, et al. Regional alterations in pro-tein expression in the dyssynchronous failing heart. Circulation. 2003;108:929-32.

16. 16.Van Oosterhout MF, Prinzen FW, Arts T, Schreuder JJ, Vanagt WY, Cleutjens JP, et al. Asynchronous electrical activation induces asymmetrical hyper-trophy of the left ventricular wall. Circulation. 1998;98:588-95.

17. 17.Rosenbaum MB, Blanco HH, Elizari MV, Lázzari JO, Davidenko JM. Electrotonic modulation of the T wave and cardiac memory. Am J Cardiol. 1982;50: 213-9.

18. 18.Sweeney MO, Hellkamp AS, Ellenbogen KA, Green-spon AJ, Freedman RA, Lee KL, et al. Adverse effect of ventricular pacing on heart failure and atrial fibrillation among patients with normal baseline QRS duration in a clinical trial of pacemaker thera-py for sinus node dysfunction. Circulation. 2003; 107:2932-7.

19. 19.Thambo JB, Bordachar P, Garrigue S, Lafitte S, Sanders P, Reuter S, et al. Detrimental ventricular remodeling in patients with congenital complete heart block and chronic right ventricular apical pacing. Circulation. 2004;110:3766-72.

20. 20.Zhang X-H, Chen H, Kai-Hang Y, Chan W-S, Lee KL, Chan H-W, et al. New-onset heart failure after per-manent right ventricular apical pacing in patients with acquired high-grade atrioventricular block and normal left ventricular function. J Cardiovasc Elec-trophysiol. 2008;19:136-41.

21. 21.Behar N, Martins RP, Daubert JC. Does paced QRS duration predict the risk of heart failure events dur-ing permanent right ventricular pacing?. Eur J Heart Fail. 2013;15:241-3.

22. 22.Hayes JJ, Sharma AD, Love JC, Herre JM, Leonen AO, Kudenchuk PJ; DAVID Investigators. Abnormal conduction increases risk of adverse outcomes from right ventricular pacing. J Am Coll Cardiol. 2006;48:1628-33.

23. 23.Shukla HH, Hellkamp AS, James EA, Flaker GC, Lee KL, Sweeney MO, et al; Mode Selection Trial (MOST) Investigators. Heart failure hospitalization is more common in pacemaker patients with sinus node dysfunction and a prolonged paced QRS duration. Heart Rhythm. 2005;2:245-51.

24. 24.Khurshid S, Epstein AE, Verdino RJ, Lin D, Goldberg LR, Marchlinski FE, et al. Incidence and predictors of right ventricular pacing-induced cardiomyopa-thy. Heart Rhythm. 2014;11:1619-25.

25. 25.Gebauer RA, Tomek V, Kubus P, Rázek V, Matejka T, Salameh A, et al. Differential effects of the site of permanent epicardial pacing on left ventricular syn-chrony and function in the young: implications for lead placement. Europace. 2009;11:1654-9.

26. 26.Janousek J, van Geldorp IE, Krupicková S, Rosenthal E, Nuget K, Tomaske M, et al. Permanent cardiac pacing in children: choosing the optimal pacing site: a multicenter study. Circulation. 2013;127:613-23.

27. 27.Cabrera Ortega M, Gonzales Morejón AE, Serrano Ricardo G. Left ventricular synchrony and function in pediatric patients with definitive pacemakers. Arq Bras Cardiol. 2013;101:410-7.

28. 28.Litwin SE, Gorman G, Huang SK. Effect of different pacing modes on left ventricular relaxation in closed chested dogs. Pacing Clin Electrophysiol. 1989;12:1070-6.

29. 29.Aoyagi T, Lizuka M, Takahashi T, Ohya T, Serizawa T, Momomura S, et al. Wall motion asynchrony pro-longs time constant of left ventricular relaxation. Am J Physiol. 1989;257:883-90.

30. 30.Dwivedi SK, Bansal S, Puri A, Makharia MK, Narain VS, Saran RK, et al. Diastolic and systolic right ven-tricular dysfunction precedes left ventricular dys-function in patients paced from right ventricular apex. Indian Pacing Electrophysiol J. 2006;6:142-52.

31. 31.Kolettis TM, Kyriakides ZS, Tsiapras D, Popov T, Paraskevaides IA, Kremastinos DT. Improved left ven-tricular relaxation during short-term right ventricu-lar outflow tract compared to apical pacing. Chest. 2000; 117:60-4.

32. 32.Hillock RJ, Mond HG. Pacing the right ventricular outflow tract septum: time to embrace the future. Europace. 2012;14:28-35.

33. 33.Mills RW, Cornelussen RN, Mulligan LJ, Strik M, Rademakers LM, Skadsberg ND, et al. Left ventricu-lar septal and left ventricular apical pacing chroni-cally maintain cardiac contractile coordination, pump function and efficiency. Cir Arrhythmia Elec-trophysiol. 2009;2:571-9.

34. 34.Tse HF, Yu C, Wong KK, Tsang V, Leung YL, Ho WY, et al. Functional abnormalities in patients with per-manent right ventricular pacing: the effect of sites of electrical stimulation. J Am Coll Cardiol. 2002;40: 1451-8.

35. 35.Shimony A, Eisenberg MJ, Filion KB, Amit G. Benefi-cial effects of right ventricular non-apical vs. apical pacing: a systematic review and meta-analysis of randomized-controlled trials. Europace. 2012;14: 81-91.

36. 36.Kypta A, Steinwender C, Kammler J, Leisch F, Hof-mann R. Long-term outcomes in patients with atrio-ventricular block undergoing septal ventricu-lar lead implantation compared with standard apical pacing. Europace. 2008;10:574-9.

37. 37.Durrer D, Van Dam RT, Freud GE, Janse MJ, Meijler FL, Arzbaecher RC. Total excitation of the isolated human heart. Circulation 1970;4:899-912.

38. 38.Tse HF, Wong KK, Siu CW, Zhang XH, Ho WY, Lau CP. Upgrading pacemaker patients with right ven-tricular apical pacing to right ventricular septal pacing improves left ventricular performance and functional capacity. J Cardiovasc Electrophysiol. 2009;20:901-5.

39. 39.Deshmukh P, Casavant DA, Romanyshyn M, Ander-son K. Permanent, direct His-bundle pacing: A novel approach to cardiac pacing in patients with normal His-Purkinje activation. Circulation. 2000;101:869-77.

40. 40.Deshmukh PM, Romanyshyn M. Direct His-bundle pacing: Present and future. Pacing Clin Electrophy-siol 2004;27:862-70.

41. 41.Catanzariti D, Maines M, Cemin C, Broso G, Marotta T, Vergara G. Permanent direct His bundle pacing does not induce ventricular dyssynchrony unlike right ventricular apical pacing. An intrapatient acute comparison study. J Interv Card Electrophy-siol. 2006;16:81-92.

42. 42.Catanzariti D, Maines M, Manica A, Angheben C, Varbaro A, Vergara G. Permanent His-bundle pacing maintains long-term ventricular synchrony and left ventricular performance, unlike conven-tional right ventricular apical pacing. Europace. 2013;15:546-53.

43. 43.Peschar M, de Swart H, Michels KJ, Reneman RS, Prinzen FW. Left ventricular septal and apex pacing for optimal pump function in canine hearts. J Am Coll Cardiol. 2003;41:1218-26.

44. 44.Tomaske M, Breithardt OA, Bauersfeld U. Pre-served cardiac synchrony and function with single-site left ventricular epicardial pacing during mid-term follow-up in paediatric patients. Europace. 2009;11:1168-76.

45. 45.van Geldorp IE, Vanagt WY, Bauersfeld U, Tomaske M, Prinzen FW, Delhaas T. Chronic left ventricular pacing preserves left ventricular function in chil-dren. Pediatr Cardiol. 2009;30:125-32.

46. 46.Vanagt WY, Prinzen FW, Delhaas T. Reversal of pacing induced heart failure by left ventricular apical pacing. N Engl J Med. 2007;357:2637-8.

47. 47.Tomaske M, Breithardt OA, Balmer C, Bauersfeld U. Successful cardiac resynchronization with single-site left ventricular pacing in children. Int J Cardiol. 2009;136:136-43.

48. 48.Kaltman J, Ro PS, Zimmerman F, Moak JP, Epstein M, Zeltser IJ, et al. Managed ventricular pacing in pediatric patients and patients with congenital heart disease. Am J Cardiol. 2008;102:875-8.