2014, Número 4
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Ann Hepatol 2014; 13 (4)
A phase 2 study of filibuvir in combination with pegylated IFN alfa and ribavirin for chronic HCV
Rodriguez-Torres M, Yoshida EM, Marcellin P, Srinivasan S, Purohit VS, Wang C, Hammond JL
Idioma: Ingles.
Referencias bibliográficas: 13
Paginas: 364-375
Archivo PDF: 157.23 Kb.
RESUMEN
Sin resumen.
REFERENCIAS (EN ESTE ARTÍCULO)
Shi ST, Herlihy KJ, Graham JP, Nonomiya J, Rahavendran SV, Skor H, Irvine R, et al. Preclinical characterization of PF-00868554, a potent nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase. Antimicrob Agents Chemother 2009; 53: 2544-52.
Wagner F, Thompson R, Kantaridis C, Simpson P, Troke P, Jagannatha S, Neelakantan S, et al. Antiviral activity of the hepatitis C virus polymerase inhibitor filibuvir administered as monotherapy in HCV genotype 1 infected patients. Hepatology 2011; 54: 50-9.
Jacobson I, Pockros PJ, Lalezari, J, Lawitz E, Rodriguez- Torres M, DeJesus E, Haas F, et al. Virologic response rates following 4 weeks of filibuvir in combination with pegylated interferon alfa-2a and ribavirin in chronically-infected HCV genotype-1 patients. Program and abstracts of the 45th Annual Meeting of the European Association for the Study of Liver (EASL); April 24-28, 2010; Vienna, Austria.
World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. Available from: http://www.wma.net/en/30publications/ 10policies/b3/index.html (accessed January 17, 2013).
Troke PJ, Lewis M, Simpson P, Gore K, Hammond J, Craig C, Westby M. Characterization of resistance to the nonnucleoside NS5B inhibitor filibuvir in hepatitis C virus-infected patients. Antimicrob Agents Chemother 2012; 56: 1331-41.
Cochran WG. Some methods of strengthening the common χ2 tests. Biometrics 1954; 10: 417-51.
Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959; 22: 719-48.
Jacobson IM, McHutchison JG, Dusheiko GM, Di Bisceglie AM, Reddy R, Bzowej NH, Marcellin P, et al. Telaprevir for previously untreated chronic hepatitis C infection. N Engl J Med 2011; 364: 2405-16.
Poordad F, McCone J Jr, Bacon BR, Bruno S, Manns M, Sulkowski M, Jacobson IM, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364: 1195-206.
McHutchison JG, Lawitz EJ, Shiffman ML, Muir AJ, Galler GW, McCone J, Nyberg LM, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009; 361: 580-93. Erratum in: N Engl J Med 2009; 361: 1027.
Fried MW, Hadziyannis SJ, Shiffman ML, Messinger D, Zeuzem S. Rapid virological response is the most important predictor of sustained virologic response across genotypes in patients with chronic hepatitis C virus infection. J Hepatol 2011; 55: 69-75.
Lawitz E, Rodriguez-Torres M, Rustgi VK, Hassanein T, Rahimy MH, Crowley CA, Freddo JL, et al. Safety and antiviral activity of ANA598 in combination with pegylated interferon á2A plus ribavirin in treatment-naive genotype-1 chronic HCV patients. Program and abstracts of the 61st Annual Meeting of the American Association for the Study of Liver Diseases; October 29-November 2, 2010; Boston, Massachusetts. Abstract 31.
Ferenci P, Nyberg A, Bernstein D, et al. PEARL III: SVR ≥ 99% after 12 wks of ABT-450/r/267 + ABT-333 ± RBV in treatment naive HCV GT1b infection. Conference on Retroviruses and Opportunistic Infections: March 3-6, 2014; Boston, Massachusettes. Abstract 29LB.