García-Rubio YZ, Lima-Gómez V

Idioma: Español
Referencias bibliográficas: 24
Paginas: 231-234
Archivo PDF: 111.20 Kb.

RESUMEN

La retinopatía diabética es una complicación crónica y específica de la diabetes mellitus que puede causar pérdida de visión como resultado de una alteración microvascular que deteriora la función macular. La fuga vascular causada por la apertura de las uniones estrechas en la barrera hematorretiniana y el aumento de la permeabilidad vascular es un importante mecanismo patogénico de edema retiniano. La unidad neurovascular es la relación física y bioquímica entre las neuronas, la glía y la vasculatura especializada de la retina, que cuando se altera contribuye a la neurodegeneración retiniana. La disfunción neural de la retina a menudo se pasa por alto cuando las anormalidades anatómicas son evidentes, lo que podría explicar la variabilidad en los resultados después del mismo tratamiento. El valor pronóstico de la disfunción de la retina requiere evaluación, ya que podría cambiar las bases fisiológicas que soporta el conocimiento terapéutico actual.

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