Mesa CS

Idioma: Español
Referencias bibliográficas: 45
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RESUMEN

Se hace una revisión de la evolución del pensamiento científico en relación a la etiología de la esquizofrenia, destacándose los estudios sobre la interacción de la genética y el medio ambiente en la aparición de esta enfermedad. Se destaca la influencia del desarrollo tecnológico en la investigación de la etiología de las enfermedades mentales así como la importancia del estudio prenatal de la esquizofrenia. Se analiza la teoría infecciosa de esta enfermedad y la programación fetal a nivel celular y molecular. Se señala la importancia de la prevención de la enfermedad a través de investigaciones dirigidas en la etapa prenatal y en consecuencia a las medidas necesarias para evitar su aparición posterior.

REFERENCIAS (EN ESTE ARTÍCULO)

1. Schizophrenia prevention. [Consultado 10 May 2014]. Disponible en http: www.schizophrenia.com/prevention.htm.

2. The cause of schizophrenia. [Consultado 28 May 2014]. Disponible en http://schizophrenia.com/hypo.php.

3. Eunice Kennedy ShriverNational Institute of Child Health and Human Development Scientific Vision Workshop on Development February 9–10, 2011 Bethesda, Maryland.

4. Eunice Kennedy ShriverNational Institute of Child Health and Human Development Scientific Vision Workshop on the Environment March 10–11, 2011 Bethesda, Maryland Workshop White Paper.

5. Gottesman II, Erlenmeyer-Kimling, L. Family and twin strategies as a head start in defining prodromes an endophenotypes for hypothetical early interventions in schizophrenia. Schizophrenia Research 2001; 51: 93-102.

6. Gilbody S, Lewis S, Lightfoot T. Methylenetetrahydrofolate reductase (MTHFR) genetic polymorphisms and psychiatric disorders: a HuGE review. Am J Epidemiol 2007; 165: 1– 13.

7. Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, et al. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Am J Psychiatry (2008) 165(4):497–506.

8. Brown AS. The environment and susceptibility to schizophrenia. Prog Neurobiol 2011; 93: 23–58.

9. Herlenius E, Lagercrantz H. Development of neurotransmitter systems during critical periods. Exp. Neurol 2004; 190: 8–21.

10. Vasung L, Huang H, Jovanov-Milosevic N, Pletikos M, Mori S, Kostovic I. Development of axonal pathways in the human fetal fronto-limbic brain: histochemical characterization and diffusion tensor imaging. J Anat 2010; 217: 400-17.

11. Bilbo SD, Schwarz JM. Early-Life Programming of Later-Life Brain and Behavior: A Critical Role for the Immune System Front Behav Neurosci. 2009; 3: 14. Published online 2009 August 24. Prepublished online 2009 June 15. doi: 10.3389/neuro.08.014.2009.

12. Haldane JBS. The rate of mutation of human genes Hereditas 1948; 35(Suppl): 267–73.

13. Burgner D, Jamieson SE, Blackwell JM. Genetic susceptibility to infectious diseases: big is beautiful, but will bigger be even better Lancet Infect Dis 2006; 6: 653–63.

14. Yolken RH, Torrey EF. Are some cases of psychosis caused by microbial agents? A review of the evidence. Molecular Psychiatry 2008; 13: 470–79.

15. Schlotz W, Phillips DI. Fetal origins of mental health: evidence and mechanisms. Brain Behav Immun. 2009; 23: 905-16.

16. Freedman R. Psychiatrists' Role in the Health of the Pregnant Mother and the Risk for Schizophrenia in Her Offspring. Am J Psychiatry 2010; 167: 239-40.

17. Mesa-Castillo S. An ultrastructural study of the temporal lobe and peripheral blood in schizophrenic patients. Rev Neurol. 2001; 33: 619-23.

18. Yolken RH, Torrey EF. Viruses, schizophrenia and bipolar disorders. Clin Microbiol Rev 1995; 8: 131-45.

19. Noll R. Historical review: autointoxication and focal infection theories of dementia praecox. World J Biol Psychiatry 2004; 5: 66–72.

20. Marie A. La Demencia. Daniel Jorro, Editor, Madrid.1908, pp. 216-38.

21. Ireland WW. Review of: on insanity after acute and chronic infectious diseases. J Mental Sci 1904; 50: 772–3.

22. Scull A. Madhouse: A Tragic Tale of Megalomania and Modern Medicine. Yale University Press: New Haven, 2005.

23. Noll R. Infectious insanities, surgical solutions: Bayard Taylor Holmes, dementia praecox and laboratory science in early 20th-century America. Part 2. Hist Psychiatry 2006; 17: 299–311.

24. Althaus J. On psychoses after influenza. J Mental Sci 1893; 39: 163–76.

25. Menninger KA. Reversible schizophrenia: a study of the implications of delirium schizophrenoides and other post-influenzal syndromes. Am J Psychiatry 1922; 1: 573– 88.

26. Kozar Z. Badania nad toksoplazmoza wsrod umyslowo chorych. Bull Inst Mar Trop Med Gdansk 1953; 5: 146–73 (Summary in English: Studies of toxoplasmosis among the mentally sick. Bull Inst Mar Trop Med Gdansk 1953; 5: 142–45.

27. Vojtechovska M, Vojtechovsky M, Petru M. Some problems of parasitology in mental patients (in Czechoslovakian). Casopis Lekaru Ceskych 1956; 95: 559–66.

28. Morozov VM. On the problem of the viral aetiology of schizophrenia. J Neuropath Psychiat, Korsakov 1954; 54: 732–34.

29. Rimon R, Halonen P. Herpes simplex virus infection and depressive illness. Dis Nerv Sys 1969; 30: 338–40.

30. Crow TJ, Ferrier IN, Johnstone EC, Macmillan JF, Owens DGC, Parry RP et al. Characteristics of patients with schizophrenia or neurological disorder and virus-like agents in cerebrospinal fluid. Lancet 1979; 1: 842–44.

31. Chacon C, Monro M, Harper I. Viral infection and psychiatric disorders. Acta Psychiat Scand 1975; 51: 101–3.

32. Torrey EF, Peterson MR. Slow and latent viruses in schizophrenia. Lancet 1973; 2: 22-4.

33. Torrey EF, Yolken RH, Winfrey CJ. Cytomegalovirus antibody in cerebrospinal fluid of schizophrenic patients detected by enzyme immunoassay. Science 1982; 216: 892–4.

34. Morozov PV (1983) (ed). Research on the Viral Hypothesis of Mental Disorders. Karger: Basel.

35. Mesa CS. Origen prenatal de la esquizofrenia. Discordancia de infección viral en gemelos idénticos. Rev. Hosp. Psiquiátrico de la Habana 2010 [consultado 17 Jul 2014]; 7(3). Disponible enhttp://www.revistahph.sld.cu/.

36. Mortensen BP, Pedersen BC, Westergaard T, Wohlfahrt J, Ewald H, Mors O et al. Effects of Family History and Place and Season of Birth on the Risk of Schizophrenia. N Engl J Med 1999; 340: 603-8.

37. Giezendanner S, Walther S, Razavi N, Van Swam C, Fisler MS, Soravia LM, et al. Alterations of White Matter Integrity Related to the Season of Birth in Schizophrenia: A DTI Study. PLoS One. 2013; 8(9): e75508. Published online 2013 September 27. doi: 10.1371/journal.pone.0075508.

38. Torrey EF, Miller J, Rawlings R, Yolken RH. Seasonality of births in schizophrenia and bipolar disorder: a review of the literature. Schizophr Res. 1997; 28: 1–38.

39. Tochigi M, Okazaki Y, Kato N, Sasaki T. What causes seasonality of birth in schizophrenia? Neurosci Res. 2004; 48: 1–11

40. Fatemi SH, Folsom TD. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr Bull 2009; 35: 528–48.

41. d'Amato T, Rochet T, Daléry J, Chauchat JH, Martin JP, Marie-Cardine M. Seasonality of birth and ventricular enlargement in chronic schizophrenia. Psychiatry Res 1994; 55: 65- 73.

42. Bennet L, and Gunn A. (2006). The fetal origins of adult mental illness. In Early Life Origins of Health and Disease (Advances in Experimental Medicine and Biology), M. Wintour-Coghlan and J. Owens, eds (New York, Springer), pp. 204–11.

43. Pearce BD. Schizophrenia and viral infection during neurodevelopment: a focus on mechanisms. Mol. Psychiatry 2001; 6: 634–46.

44. Brown AS, Derkits EJ. Prenatal infection and schizophrenia: a review of epidemiologic and translational studies. Am J Psychiatry 2010; 167:261-80.

45. Uher R. Gene–Environment Interactions in Severe Mental Illness. Front Psychiatry 2014; 5: 48.