Thompson BMR, Rosas SG, Lara LM, Merino GJL, Moreno SHN, Morán ME, Rodríguez GJ, Calderón RG, Rangel GSI, Salazar SJ, Núñez CR, González BJA

Idioma: Español
Referencias bibliográficas: 51
Paginas: 52-61
Archivo PDF: 519.12 Kb.

RESUMEN

Los casos de sepsis siguen causando altas morbilidad y mortalidad en pacientes de las unidades de cuidados intensivos, ello ha provocado el uso temprano y empírico de antibióticos de amplio espectro que ha conllevado a la selección de cepas multirresistentes, a la descompensación de la flora comensal en la persona y al aumento de complicaciones que pueden culminar en la muerte del paciente. El desarrollo de técnicas moleculares y su incursión paulatina a los hospitales brinda una alternativa diagnóstica rápida, sensible y específica para identificar al agente causal, determinar la sensibilidad o resistencia a los antimicrobianos y discriminar efectivamente la flora contaminante. En el presente trabajo se exponen los resultados de muestras remitidas por el Departamento de Epidemiología al laboratorio de Medicina Genómica para integrar el diagnóstico de un probable cuadro de sepsis en un período comprendido entre mayo de 2012 a septiembre de 2013, donde se recibieron un total de 25 muestras (18 adultos y 7 neonatos) y los resultados se obtuvieron en 72 horas. El 80% de las muestras presentaron infecciones polimicrobianas y el Stenotrophomonas maltophilia fue el principal agente identificado, incluso en cuatro de los casos estuvo presente como el único microorganismo en la muestra.

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