2013, Número 4
<< Anterior Siguiente >>
Neumol Cir Torax 2013; 72 (4)
Proceso diagnóstico de la tromboembolia pulmonar
Morales-Blanhir JE, Rosas-Romero MJ, Campos-Cerda R, Becerra-Lara JJ
Idioma: Español
Referencias bibliográficas: 54
Paginas: 323-332
Archivo PDF: 327.49 Kb.
RESUMEN
La enfermedad tromboembólica venosa es un conjunto de patologías con un proceso fisiopatológico común. La tromboembolia pulmonar es la manifestación de esta entidad en la circulación pulmonar. Su presentación es variable y requiere de alta sospecha clínica para su abordaje. La importancia de las manifestaciones clínicas incide directamente en la probabilidad de demostrar la enfermedad; es decir, la probabilidad preprueba de cursar con ella. Los estudios auxiliares de gabinete y laboratorio permiten estratificar a los pacientes de acuerdo al riesgo y gravedad de la misma. Existen herramientas que permiten confirmar la enfermedad, su empleo depende de las características clínicas del paciente. El juicio clínico y su complemento con algoritmo de estudio permiten establecer el diagnóstico, delimitar propuestas de tratamiento y estimar el curso de la enfermedad. La coexistencia de otras manifestaciones de la enfermedad tromboembólica venosa en la circulación venosa periférica incrementa la probabilidad de cursar con tromboembolismo pulmonar. El antecedente de comórbidos o la sospecha de esta patología en grupos especiales, son un reto para el clínico al confirmar su existencia.
REFERENCIAS (EN ESTE ARTÍCULO)
Cabrera-Rayo A, Nellen-Hummel H. Epidemiología de la enfermedad tromboembólica venosa. Gac Méd Méx 2007;143(S1):3-5.
Kasper W, Konstantinides S, Geibel A, et al. Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol 1997;30:1165-1171.
Guidelines on diagnosis and management of acute pulmonary embolism. Task Force on Pulmonary Embolism, European Society of Cardiology. Eur Heart Journal 2000;21:1301-1336.
Jerjes-Sánchez C, Elizalde JJ, Sandoval J, et al. Diagnóstico, estratificación y tratamiento de la tromboembolia pulmonar aguda. Arch Inst Cardiol Mex 2004;74(Supl 3):S547-S585.
Morales-Blanhir JE, Salas-Pacheco JL, Rosas-Romero M de J, Valle-Murillo MA. Diagnóstico de tromboembolia pulmonar. Arch Cardiol Mex 2011;81:126-136.
Villagómez A, Alcántar E, Avelar F, et al. Guías para el diagnóstico, prevención y tratamiento de la enfermedad tromboembólica venosa. Med Inter Mex 2006;22:S1-S37.
Wells PS, Anderson DR, Rodger M, et al. Derivation of a simple clinical model to categorize patients probability of pulmonary embolism: increasing the models utility with the SimpliRED D-Dimer. Thromb Haemost 2000;83:416-420.
The urokinase pulmonary embolism trial. A national cooperative study. Circulation 1973;47(2 Suppl):II1-II108.
Value of the ventilation/perfusion scan in acute pulmonary embolism. Results of the prospective investigation of pulmonary embolism diagnosis (PIOPED). The PIOPED Investigators. JAMA 1990;263:2753-2759.
Kucher N, Walpoth N, Wustmann K, Noveanu M, Gertsch M. QR in V1--an ECG sign associated with right ventricular strain and adverse clinical outcome in pulmonary embolism. Eur Heart J 2003;24:1113-1119.
Piazza G, Goldhaber SZ. Acute pulmonary embolism: part I: epidemiology and diagnosis. Circulation 2006;114;e28-e32.
Tapson VF, Carroll BA, Davidson BL, et al. The diagnostic approach to acute venous thromboembolism. Clinical practice guideline. American Thoracic Society. Am J Respir Crit Care Med 1999;160:1043-1066.
Lualdi JC, Goldhaber SZ. Right ventricular dysfunction after acute pulmonary embolism: pathophysiologic factors, detection, and therapeutic implications. Am Heart J 1995;30:1276-1282.
Tapson VF. Diagnosing and managing acute pulmonary embolism: role of cardiac troponins. Am Heart J 2003;145:751-753.
Konstantinides S, Geibel A, Olschewski M, et al. Importance of cardiac troponins I and T in risk stratification of patients with acute pulmonary embolism. Circulation 2002;106:1263-1268.
Douketis JD, Crowther MA, Stanton EB, Ginsberg JS. Elevated cardiac troponin levels in patients with submassive pulmonary embolism. Arch Intern Med 2002;162:79-81.
Douketis JD, Leeuwenkamp O, Grobara P, et al. The incidence and prognostic significance of elevated cardiac troponins in patients with submassive pulmonary embolism. J Thromb Haemost 2005;3:508-513.
Pruszczyk P, Bochowicz A, Torbicki A, et al. Cardiac troponin T monitoring identifies high-risk group of normotensive patients with acute pulmonary embolism. Chest 2003;123:1947-1952.
Kostrubiec M, Pruszczyk P, Bochowicz A, et al. Biomarker-based risk assessment model in acute pulmonary embolism. Eur Heart J 2005;26:2166-2172.
Mueller C, Scholer A, Laule-Kilian K, et al. Use of B-type natriuretic peptide in the evaluation and management of acute dyspnea. N Engl J Med 2004;350:647-654.
Kucher N, Printzen G, Goldhaber SZ. Prognostic role of brain natriuretic peptide in acute pulmonary embolism. Circulation 2003;107:2545-2547.
Kucher N, Printzen G, Doernhoefer T, Windecker S, Meier B, Hess OM. Low pro-brain natriuretic peptide levels predict benign clinical outcome in acute pulmonary embolism. Circulation 2003;107:1576-1578.
Wolde M, Tulevski II, Mulder JW, et al. Brain natriuretic peptide as a predictor of adverse outcome in patients with pulmonary embolism. Circulation 2003;107:2082-2084.
Söhne M, Ten Wolde M, Büller HR. Biomarkers in pulmonary embolism. Curr Opin Cardiol 2004;19:558-562.
Invasive and noninvasive diagnosis of pulmonary embolism. Preliminary results of the Prospective Investigative Study of Acute Pulmonary Embolism Diagnosis (PISA-PED). Chest 1995;107(1 Suppl):33S-38S.
Goldhaber SZ, Visani L, De Rosa M. Acute pulmonary embolism: clinical outcomes in the Internacional Cooperative Pulmonary Embolism Registry (ICOPER). Lancet 1999;353:1386-1389.
Torbicki A, Perrier A, Konstantinides S, et al. Guidelines on the diagnosis and management of acute pulmonary embolism. The Task Force for the Diagnosis and Management of Acute Pulmonary Embolism of the European Society of Cardiology (ESC). Eur Heart J 2008;29:2276-2315.
Kimura-Hayama E, Canseco-León N, Santiago-Serra R. Multidetector computed angiography: a new era in the evaluation of pulmonary thromboembolism. Arch Cardiol Mex 2011;81:137-150.
Stein PD, Hull RD. Multidetector computed tomography for the diagnosis of acute pulmonary embolism. Curr Opin Pulm Med 2007;13:384-388.
Kuriakose J, Patel S. Acute pulmonary embolism. Radiol Clin North Am 2010;48:31-50.
Piazza G. Submassive Pulmonary Embolism. JAMA 2013;309:171-180.
Becattini C, Agnelli G, Vedovati MC, et al. Multidetector computed tomography for acute pulmonary embolism: diagnosis and risk stratification in a single test. Eur Heart J 2011;32:1657-1663.
Moores LK, King CS, Holley AB. Current approach to the diagnosis of acute nonmassive pulmonary embolism. Chest 2011;140:509-518.
Miles S, Rogers KH, Thomas P, et al. A comparision of single-photon emission CT Lung Scintigraphy and CT pulmonary angiography for the diagnosis of pulmonary embolismo. Chest 2009;136:1546-1553.
Salaun PY, Couturaud F, Le Duc-Pennec A, et al. Noninvassive diagnosis of pulmonary embolismo. Chest 2011;139:1294-1298.
Sáenz de la Calzada C, Sánchez-Sánchez V, Velázquez-Martín M, et al. Guías de Práctica Clínica de la Sociedad Española de Cardiología en tromboembolismo e hipertensión pulmonar. Rev Esp Cardiol 2001;54:194-210.
Carlbom DJ, Davidson BL. Pulmonary embolism in the critically ill. Chest 2007;32:313-324.
Meaney JF, Weg JG, Chenever TL, Sanfford-Johnson D, Hamilton BH, Prince MR. Diagnosis of pulmonary embolism with magnetic resonance angiography. N Engl J Med 1997;336:1422-1427.
Rahimtoola A, Bergin JD. Acute pulmonary embolism: an update on diagnosis and management. Curr Probl Cardiol 2005;30:61-114.
Brown H, Hiett A. Deep vein thrombosis and pulmonary embolism in pregnancy: diagnosis, complications and management. Clin Obstet Gynecol 2010;53:345-359.
Wildberger JE, Mahken AH, Das M, et al. CT imaging in acute pulmonary embolism: diagnostic strategies. Eur Radiol 2005;15:919-929.
Quiroz R, Kucher N, Schoepf UJ, et al. Right ventricular enlargement on chest computed tomogragraphy: pronostic role in acute pulmonary embolism. Circulation 2004;109:2401-2404.
Schoepf UJ, Kucher N, Kipfmueller F, Quiroz R, Costello P, Goldhaber SZ. Right ventricular enlargement on chest computed tomography: a predictor of early death in acute pulmonary embolism. Circulation 2004;110:3276-3280.
Fedullo P, Tapson V. Clinical practice. The evaluation of suspected pulmonary embolism. N Engl J Med 2003;349:1247-1256.
Anderson J, Jenq T, Bain M, et al. Diagnosis of posttraumatic pulmonary embolism: is chest computed tomographic angiography acceptable? J Trauma 2003;54:472-477.
Wood KE. Major pulmonary embolism. Review of a pathophysiologic approach to the golden hour of hemodynamically significant pulmonary embolism. Chest 2002;121:877-905.
Reittner P, Coxson HO, Nakano Y, et al. Pulmonary embolism: comparison of gadolinium-enhanced MR angiography with contrast-enhanced spiral CT in a porcine model. Acad Radiol 2001;8:343-350.
Oudkerk M, van Beek EJ, Wielopolski P, et al. Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: prospective study. Lancet 2002;359:1643-1647.
Uresandi F, Blanquer J, Conget F, et al. Guidelines for the diagnosis, treatment and follow-up of pulmonary embolism. Arch Bronconeumol 2004;40:580-594.
Goldhaber SZ. Echocardiography in the management of pulmonary embolism. Ann Intern Med 2002;136:691-700.
McConnell MV, Solomon SD, Rayan ME, Come PC, Goldhaber SZ, Lee RT. Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism. Am J Cardiol 1996;78:469-473.
Kucher N, Rossi E, De Rosa M, Goldhaber SZ. Prognostic role of echocardiography among patients with acute pulmonary embolism and a systolic arterial pressure of 90 mm Hg or higher. Arch Intern Med 2005;165:1777-1781.
Kjaergaard J, Krogsgaard SB, Lund JO, Hassager C. Quantitative measures of right ventricular dysfunction by echocardiography in the diagnosis of acute nonmassive pulmonary embolism. J Am Soc Echocardiog 2006;19:1264-1271.
Ramos RS, Salem BI, Haikal M, Goudas-Coordes CK, Leidenfost R. Critical role of pulmonary angiography in the diagnosis of pulmonary emboli following cardiac surgery. Cathet Cardiovasc Diagn 1995;36:112-117.