2013, Número 4
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Aten Fam 2013; 20 (4)
¿Antimicrobianos para el síndrome de intestino irritable?
Frati-Munari AC
Idioma: Español
Referencias bibliográficas: 33
Paginas: 123-126
Archivo PDF: 339.39 Kb.
RESUMEN
El síndrome de intestino irritable (SII) es un trastorno funcional crónico del tubo digestivo que cursa con molestia o dolor abdominal, diarrea o constipación, distensión abdominal y otros síntomas intestinales. Aunque no se conoce una causa única del SII, recientemente se ha enfatizado la participación de las bacterias en su fisiopatología, sobre todo por la presentación del sii después de infecciones gastrointestinales. La presencia de sobrecrecimiento bacteriano en el intestino delgado y modificaciones de la microbiota intestinal pueden provocar microinflamación intestinal, alteraciones de la motilidad intestinal, hipersensibilidad visceral y producción excesiva de gas, que serían los causantes de los síntomas. La respuesta clínica prolongada después del uso de antibióticos no absorbibles de amplio espectro, especialmente la rifaximina, apoya el concepto y ofrece un tratamiento adicional para muchos pacientes.
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