2013, Número 2
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Rev Mex Neuroci 2013; 14 (2)
Heredabilidad de los subtipos de enfermedad vascular isquémica
Millán CMR, Espinosa SL
Idioma: Español
Referencias bibliográficas: 10
Paginas: 61-62
Archivo PDF: 516.29 Kb.
FRAGMENTO
En los últimos años, los estudios de asociación de genoma
amplio (GWAS) han representado una nueva herramienta para
investigar la estructura genética de enfermedades con herencia
compleja. El ensayo de varios cientos de miles de
polimorfismos de nucleótido único (SNP) en miles de individuos
no relacionados ha permito identificar y replicar numerosas
asociaciones de variaciones genéticas comunes en al
menos un ciento de estas enfermedades.
REFERENCIAS (EN ESTE ARTÍCULO)
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Mohanty S, Santangeli P, Bai R, DI Biase L, Mohanty P et al. Variant rs2200733 on chromosome 4q25 confers increased risk of atrial fibrillation: evidence from a meta-analysis. J Cardiovasc Electrophysiol 2013; 24: 155-61.