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2013, Número 3

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Gac Med Mex 2013; 149 (3)


Los sexoesteroides y la diferenciación sexual cerebral: ¿la contaminación de xenoestrógenos modificaría la estructura social humana?

Zhang L, Neme-Bechara V, Escobar A, Irles C

Idioma: Español
Referencias bibliográficas: 81
Paginas: 325-333
Archivo PDF: 102.82 Kb.


RESUMEN

Los xenoestrógenos (XE), también llamados «químicos endocrinoperturbadores», son productos industriales que se unen a receptores endógenos de los sexoesteroides (SE), hormonas que, además de regular fundamentalmente la función reproductiva, influyen determinantemente en la estructura y la función del cerebro. Los XE, al actuar como agonistas estrogénicos débiles y/o antagonistas androgénicos, pueden alterar el dimorfismo sexual cerebral. En este artículo, revisaremos primero los conocimientos actuales sobre la influencia de los SE sobre el funcionamiento cerebral; posteriormente, examinaremos las evidencias científicas sobre los efectos conductuales de los XE en mamíferos; finalmente, analizaremos los posibles impactos de esta contaminación industrial sobre la estructura de la sociedad humana.


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