medigraphic.com

2012, Número 4

<< Anterior Siguiente >>

Rev Med Inst Mex Seguro Soc 2012; 50 (4)


Cirugía en enterocolitis necrotizante en niños. Supervivencia y morbilidad

García H, Franco-Gutiérrez M, Gutiérrez-Hernández JI

Idioma: Español
Referencias bibliográficas: 40
Paginas: 427-436
Archivo PDF: 109.41 Kb.


RESUMEN

Introducción: la enterocolitis necrotizante es una enfermedad adquirida; de quienes desarrollan la enfermedad, cerca de 90 % es prematuro. Nuestro objetivo fue identificar la supervivencia y las causas de morbilidad durante el primer año de vida en niños con enterocolitis necrotizante y cirugía en la etapa neonatal.
Métodos: se estudiaron 32 niños con enterocolitis necrotizante (19 fallecidos y 13 supervivientes) que recibieron tratamiento quirúrgico en el periodo neonatal. Se registraron variables perinatales, tipo de cirugía, hallazgos quirúrgicos, morbilidad y supervivencia en la etapa neonatal y en el primer año de vida.
Resultados: a todos los niños se les realizó laparotomía, excepto a tres fallecidos en quienes se instaló sistema de drenado peritoneal. Las principales morbilidades en el primer año de vida fueron colestasis y obstrucción intestinal. La supervivencia en la etapa neonatal fue de 78 % y en el primer año de vida de 40.6 %.
Conclusiones: la morbilidad en el primer año se relacionó con la cirugía. La supervivencia fue alta en la etapa neonatal y descendió en el primer año de vida.



REFERENCIAS (EN ESTE ARTÍCULO)

  1. Jesse N, Neu J. Necrotizing enterocolitis: relationship to innate immunity, clinical features, and strategies for prevention. Neoreviews 2006;7(3):143-150.

  2. Walsh MC, Kliegman RM, Hack M. Severity of necrotizing enterocolitis: Influence on outcome at 2 years of age. Pediatrics 1989;84(5):808-814.

  3. Simon NP. Follow-up for infants with necrotizing enterocolitis. Clin Perinatol 1994;21(2):411-424.

  4. Kliegman RM, Fanaroff AA. Necrotizing enterocolitis. N Engl J Med 1984;310(17):1093-1103.

  5. Lin PW, Stoll BJ. Necrotising enterocolitis. Lancet 2006;368 (9543):1271-1283.

  6. Holman RC, Stoll BJ, Clarke MJ, Glass RI. The epidemiology of necrotizing enterocolitis infant mortality in the United States. Am J Public Health 1997;87(12):2026- 2031.

  7. Neu J, Walker WA. Necrotizing enterocolitis. N Engl J Med 2011;364(3):255-264.

  8. Stoll BJ. Epidemiology of necrotizing enterocolitis. Clin Perinatol 1994;21(2):205-218.

  9. Llanos AR, Moss ME, Pinzón MC, Dye T, Sinkin RA, Kendig JW. Epidemiology of neonatal necrotising enterocolitis: a population-based study. Pediatr Perinat Epidemiol 2002; 16(4):342-349.

  10. Guthrie SO, Gordon PV, Thomas V, Thorp JA, Peabody J, Clark RH. Necrotizing enterocolitis among neonates in the United States. J Perinatol 2003;23(4):278-285.

  11. Lemons JA, Bauer CR, Oh W, Korones SB, Papile L, Stoll BJ, et al. Very low birth weight outcomes of the National Institute of Child Health and Human Development Neonatal Research Network, January 1995 through December 1996. Pediatrics 2001;107(1):e1

  12. Fanaroff AA, Hack M, Walsh MC. The NICHD neonatal research network: changes in practice and outcomes during the first 15 years. Semin Perinatol 2003;27(4):281-287.

  13. Berseth CL. Feeding strategies and necrotizing enterocolitis. Curr Opin Pediatr 2005;17(2):170-173.

  14. Maayan-Metzger A, Itzchak A, Mazkereth R, Kuint J. Necrotizing enterocolitis in full-term infants: case-control study and review of the literature. J Perinatol 2004;24(8):494-499.

  15. Wilson R, del Portillo M, Schmidt E, Feldman RA, Kanto WP Jr. Risk factors for necrotizing enterocolitis in infants weighing more than 2,000 grams at birth: case-control study. Pediatrics 1983;71(1):19-22.

  16. McElhinney DB, Hedrick HL, Bush DM, Pereira GR, Stafford PW, Gaynor JW, et al. Necrotizing enterocolitis in neonates with congenital heart disease: risk factors and outcomes. Pediatrics 2000;106(5):1080-1087.

  17. Ostlie DJ, Spilde TL, St Peter SD, Sexton N, Millar KA, Sharp RJ, et al. Necrotizing enterocolitis in full-term infants. J Pediatr Surg 2003;38(7):1039-1042.

  18. Blakely ML, Lally KP, McDonald S, Brown RL, Barnhart DC, Ricketts RR, et al. Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network. Ann Surg 2005; 241(6):984-994.

  19. Henry MC, Lawrence Moss R. Surgical therapy for necrotizing enterocolitis: bringing evidence to the bedside. Semin Pediatr Surg 2005;14(3):181-190.

  20. Anveden-Hertzberg L, Gauderer MW. Surgery is safe in very low birthweight infants with necrotizing enterocolitis. Acta Paediatr 2000;89(2):242-245.

  21. Ehrlich PF, Sato TT, Short BL, Hartman GE. Outcome of perforated necrotizing enterocolitis in the very low-birth weight neonate may be independent of the type of surgical treatment. Am Surg 2001;67(8):752-756.

  22. Voss M, Moore SW, van der Merwe I, Pieper C. Fulminanting necrotizing enterocolitis: outcome and prognostic factors. Pediatr Surg Int 1998;13(8):576-580.

  23. Snyder CL, Gittes GK, Murphy JP, Sharp RJ, Ashcraft KW, Amoury RA. Survival after necrotizing enterocolitis in infants weighing less than 1,000 g: 25 years’ experience at a single institution. J Pediatr Surg 1997;32(3): 434-437.

  24. de Souza JC, da Motta UI, Ketzer CR. Prognostic factors of mortality in newborns with necrotizing enterocolitis submitted to exploratory laparotomy. J Pediatr Surg 2001; 36(3):482-486.

  25. Horwitz JR, Lally KP, Cheu HW, Vázquez WD, Grosfeld JL, Ziegler MM. Complications after surgical intervention for necrotizing enterocolitis: a multicenter review. J Pediatr Surg 1995;30(7):994-998.

  26. Janik JS, Ein SH, Mancer K. Intestinal stricture after necrotizing enterocolitis. J Pediatr Surg 1981;16(4):438-443.

  27. Petty JK, Ziegler MM. Operative strategies for necrotizing enterocolitis: the prevention and treatment of short-bowel syndrome. Semin Pediatr Surg 2005;14(3):191-198.

  28. Bell MJ, Ternberg JL, Feigin RD, Keating JP, Marshall R, Barton L, et al. Neonatal necrotizing enterocolitis: therapeutic decisions based upon clinical staging. Ann Surg 1978;187(1):1-7.

  29. Neu J. The “myth” of asphyxia and hypoxia-ischemia as primary causes of necrotizing enterocolitis. Biol Neonate 2005;87(2):97-98.

  30. Nowicki PT, Nankervis CA. The role of the circulation in the pathogenesis of necrotizing enterocolitis. Clin Perinatol 1994;21(2):219-234.

  31. Demestre X, Ginovart G, Figueras-Aloy J, Porta R, Krauel X, García-Alix A, et al. Peritoneal drainage as primary management in necrotizing enterocolitis: a prospective study. J Pediatr Surg 2002;37(11):1534-1539.

  32. Camberos A, Patel K, Applebaum H. Laparotomy in very small premature infants with necrotizing enterocolitis or focal intestinal perforation: postoperative outcome. J Pediatr Surg 2002;37(12):1962-1965.

  33. Moss L, Dimmitt RA, Barnhart DC, Sylvester KG, Brown RL, Powell DM, et al. Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation. N Engl J Med 2006;354(21):2225-2234.

  34. Henry MCW, Moss RL. Laparotomy versus peritoneal drainage for perforated necrotizing enterocolitis. Neoreviews 2006;7(9):456-462.

  35. Pratt CA, García MG, Kerner JA Jr. Nutritional management of neonatal and infant liver disease. Neoreviews 2001;2 (9):215-222.

  36. Chwals WJ, Blakely ML, Cheng A, Neville HL, Jaksic T, Cox CS Jr, et al. Surgery-associated complications in necrotizing enterocolitis: a multiinstitutional study. J Pediatr Surg 2001;36(11):1722-1724

  37. Sharma R, Tepas JJ 3rd, Mollitt DL, Pieper P, Wludyka P. Surgical management of bowel perforations and outcome in very low-birth-weight infants (< or = 1,200 g). J Pediatr Surg 2004;39(2):190-194.

  38. Sigalet DL. Short bowel syndrome in infants and children: an overview. Semin Pediatr Surg 2001;10(2):49-55.

  39. Hintz SR, Kendrick DE, Stoll BJ, Vohr BR, Fanaroff AA, Donovan EF, et al. Neurodevelopmental and growth outcomes of extremely low birth weight infants after necrotizing enterocolitis. Pediatrics 2005;115(3):696-703.

  40. Ladd AP, Rescorla FJ, West KW, Scherer LR 3rd, Engum SA, Grosfeld JL. Long-term follow-up after bowel resection for necrotizing enterocolitis: factors affecting outcome. J Pediatr Surg 1998;33(7):967-972.




2020     |     www.medigraphic.com