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2003, Número 4

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Rev Med Hosp Gen Mex 2003; 66 (4)


Aspectos genéticos de la hipertensión arterial

Carlos ZJ, Kofman-Alfaro S

Idioma: Español
Referencias bibliográficas: 53
Paginas: 218-223
Archivo PDF: 93.06 Kb.


RESUMEN

La hipertensión es un problema de salud pública que afecta a aproximadamente 25% de la población en sociedades industrializadas y conlleva un riesgo elevado de complicaciones cardiovasculares y renales. En los últimos años, el estudio genético de algunos síndromes hereditarios que causan hipertensión o hipotensión ha permitido definir algunos mecanismos moleculares que regulan la presión sanguínea en el humano. Sin embargo, la hipertensión esencial o primaria, que es la que se presenta en más del 90% de sujetos hipertensos, es causada por una combinación variable de factores genéticos poco conocidos y de factores ambientales. En este trabajo se revisan los datos epidemiológicos y genéticos que han sido identificados recientemente en el estudio de la hipertensión arterial.


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