Meza U, Romero-Méndez AC, Licón Y, Sánchez-Armáss S

Idioma: Español
Referencias bibliográficas: 36
Paginas: 125-134
Archivo PDF: 527.05 Kb.

RESUMEN

La membrana plasmática es la estructura que delimita a la célula. Inicialmente conceptualizada como una barrera inerte, divisoria del interior y exterior celular, en la actualidad se le reconoce como un elemento dinámico y fundamental en el mantenimiento de la integridad de la célula. Su plétora de componentes lipídicos y proteicos propicia su participación en muy diversos e importantes procesos por ejemplo: transporte y permeabilidad selectiva de sustancias e iones, excitabilidad, movilidad, diferenciación, exocitosis, reconocimiento intercelular y transducción de señales extracelulares. La presente revisión incluye un breve recuento de los principales modelos que han conducido a la concepción actual de su estructura y de sus propiedades funcionales y destaca las implicaciones del modelo vigente de balsas de membrana en procesos de señalización intracelular.

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