2012, Número 2
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Rev cubana med 2012; 51 (2)
Primer caso de leucemia mieloide aguda tratado en Cuba con altas dosis de antraciclinas en la inducción
Hernández CC, Núñez QA, Rodríguez FY, Carnot UJ, Chávez MR, Moya PI
Idioma: Español
Referencias bibliográficas: 37
Paginas: 197-204
Archivo PDF: 42.02 Kb.
RESUMEN
La leucemia mieloide aguda abarca un heterógeneo espectro de enfermedades, de naturaleza maligna y clonal, que representan un reto formidable para la medicina moderna. Con la excepción de la leucemia promielocítica, los resultados terapéuticos alcanzados continúan siendo desalentadores. Recientemente han surgido datos que demuestran mejores resultados con el uso de altas dosis de antraciclinas en la inducción. Se presentó el primer caso en Cuba, en cuya inducción se utilizó la rubidomicina a 100 mg/m2 por 3 d, más el arabinósido de citosina a 100 mg/m2 por 7 d, ambos en infusión endovenosa continua. La evolución clínica es satisfactoria hasta el momento. Se revisó brevemente la literatura médica al respecto.
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