Floriano-Sánchez E, Castro-Marín M, Cárdenas-Rodríguez N, López-Silvestre JC, Zapata-Villalba MA, Campos-Salcedo JG, Estrada-Carrasco CE, Mendoza Álvarez LA, Rosas-Hernandez H, Paredes-Calva C, Reyes-Equihua JL, Sedano-Lozano A

Idioma: Español
Referencias bibliográficas: 22
Paginas: 45-49
Archivo PDF: 352.89 Kb.

RESUMEN

Introducción: El cáncer de próstata (CaP) es la segunda causa de muerte en hombres, por cáncer a nivel mundial. Se están estudiando varios citocromos en CaP. Para el caso del CYP4F11 Y 8A1, existen pocos estudios en la literatura. En este estudio, se determinó la presencia del CYP4F11 y 8A1 en CaP e hiperplasia prostática benigna (HPB).
Material y método: Se obtuvieron 32 muestras de HPB y 32 de CaP. Se estandarizaron las condiciones, para detectar por inmunohistoquímica la presencia de CYP4F11 y CYP8A1 en los tejidos.
Resultados: El CYP4F11 y 8A1 no se expresaron en HPB.
Conclusiones: Los resultados anteriores sugieren que CYP4F11 y 8A1 podrían ser utilizados como factores pronósticos y/o detección temprana, realizando estudios en biopsias de pacientes sospechosos de CaP.

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