2012, Número 1
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Rev Mex Cardiol 2012; 23 (1)
Espasmo coronario dinámico. ¿Nueva entidad o presencia de un viejo problema?
Galeano-Ricaño HA
Idioma: Español
Referencias bibliográficas: 29
Paginas: 20-26
Archivo PDF: 123.16 Kb.
RESUMEN
Es bien conocido el hecho de que la angioplastia coronaria transluminal percutánea (ACTP) y el implante de stent provocan daño endotelial. En ocasiones es tan severo que se manifiesta por vasoconstricción coronaria persistente, condicionando isquemia miocárdica (clínica, eléctrica y/o enzimática). Sin embargo, es posible que se manifieste de otra forma: espasmo coronario dinámico. Se presentan dos casos con varias similitudes entre sí: evolución tórpida con sospecha de oclusión del stent; intervencionismo con agresión endotelial (ultrasonido intracoronario e implante de stent); imagen angiográfica de espasmo arterial coronario dinámico, confundido con puente muscular. El espasmo coronario dinámico se puede definir como la vasoconstricción oclusiva dinámica de un segmento coronario epicárdico, en una arteria que ha sido sometida a intervencionismo. Habría que diferenciarlo del no reflujo, provocado por la oclusión total de la arteria intervenida del espasmo inducido por catéter, pero sobre todo, del puente muscular. En ambos casos se reportó como puente muscular, sin embargo, en el estudio diagnóstico no se observaba esta imagen. El motivo del presente trabajo es llamar la atención a la comunidad médica, específicamente al médico intervencionista, sobre una imagen que puede ser un factor pronóstico y terapéutico (tratamiento con calcio-antagonistas y nitratos, uso de marcadores séricos o seguimiento más estrecho), en la evolución de los pacientes sometidos a intervencionismo coronario.
REFERENCIAS (EN ESTE ARTÍCULO)
Topol EJ. Cardiología Intervencionista. Tercera edición, México: McGraw-Hill Interamericana. 2000: 193-221.
Sinclair IN, McCabe CH, Sipperly ME. Predictors, therapeutic options, and long-term outcome of abrupt reclosure. Am J Cardiol 1988; 61: 61G.
de Feyter PJ, van den Brand M, Jaarman GJ et al. Acute coronary artery occlusion during and after percutaneous transluminal coronary angioplasty: Frequency, prediction, clinical course, management, and follow-up. Circulation 1991; 83: 927-936.
Lincoff AM, Popma JJ, Ellis SG et al. Abrupt vessel closure complicating coronary angioplasty: Clinical, angiographic, and therapeutic profile. J Am Coll Cardiol 1992; 19: 926-935.
Ellis SG, Roubin GS, King SB et al. Angiopraphic and clinical predictor of acute closure after native vessel coronary angioplasty. Circulation 1988; 77: 372-379.
Detre KM, Holmes DR, Holubkov R et al. Incidence and consequences of periprocedural occlusion. The 1985-1986 National, Heart, Lung, and Blood Institute percutaneous transluminal coronary angioplasty registry. Circulation 1990; 82: 739-750.
Simpfendorfer C, Belardi J, Bellamy G et al. Frequency management and follow-up of patients with acute coronary occlusions after percutaneous transluminal coronary angioplasty. Am J Cardiol 1987; 59: 267.
Goldbaum T, DeSciascio G, Cowley MJ, Vetrovec GW. Early occlusion following successful coronary angioplasty: Clinical and angiographic observations. Cathet Cardiovasc Diagn 1989; 17: 22.
Krucoff MW, Parente AR, Bottner RK et al. Stability of multilead ST-segment “fingerprints” over time after percutaneous transluminal coronary angioplasty and its usefulness in detecting reocclusion. Am J Cardiol 1988; 61: 1232-1237.
Bush HS, Ferguson JJ, Angelini P, Willerson JE. Twelve-lead electrocardiographic evaluation of ischemia during percutaneous transluminal coronary angioplasty and its correlation with acute reocclusion. Am Heart J 1991; 121: 1591-1599.
Krucoff MW, Jackxon YR, Kehoe KM, Kent MK. Quantitative and qualitative ST segment monitoring during and after percutaneous transluminal coronary angioplasty. Circulation 1990; 81: IV-20-IV-26.
Tenaglia AN, Fortin DF, Frid DJ et al. Long-term outcome following successful reopening of abrupt closure after coronary angioplasty. Am J Cardiol 1993; 72: 21-25.
Abdelmeguid AE, Whitlow PL, Sapp SK et al. Long-term outcome of transient uncomplicated in-laboratory coronary artery closure. Circulation 1995; 91: 2733-2741.
Topol EJ, Ferguson JJ, Weisman HE et al. Long-term protection from myocardial ischemic events in a randomized trial of brief integrin b, blockade with percutaneous coronary intervention. JAMA 1997; 278: 479-484.
Abdelmeguid AE, Ellis SG, Sapp SK et al. Defining the appropriate thershold of creatine kinase elevation after percutaneous intervention. Am Heart J 1996; 131: 1097-1105.
Jennferadgme AA, Athewm TPM, Arbinson DMTH. Periprocedural Creatine Kinase-MB Elevations: Long-term impact and clinical implications. Clin Cardiol 1999; 22: 257-265.
Sherman CT, Litvack F, Grundfest W et al. Coronary angioscopy in patients with unstable angina pectoris. N Eng J Med 1986; 315: 913-919.
Mabin TA, Holmes DR, Smith HC. Intracoronary thrombus: Role in coronary occlusion complicating percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1985; 5: 198.
Holmes DRJ, Holubkov R, Vlietstra RE et al. Comparison of complications during percutaneous transluminal coronary angioplasty from 1977 to 1981 and from 1985 to 1986: The National Heart Lung, and Blood Institute Percutaneous Transluminal Coronary Angioplasty Registry. J Am Coll Cardiol 1988; 12: 1149-1155.
Togni M, Windecker S, Cocchia R et al. Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction. J Am Coll Cardiol 2005; 46: 231-236.
Hofma SH, van der Giessen WJ, van Dalen BM et al. Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation. Eur Heart J 2006; 27: 166-170.
Fuke S, Maekawa K, Kawamoto K et al. Impaired endothelial vasomotor function after sirolimus-eluting stent implantation. Circ J 2007; 71: 220-225.
Obata J, Kitta Y, Takano H et al. Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction. J Am Coll Cardiol 2007; 50: 1305-1309.
Shin DI, Kim PJ, Seung KB et al. Drug-eluting stent implantation could be associated with long-term coronary endothelial dysfunction. Comparison between sirolimus-eluting stent and paclitaxel-eluting stent. Int Heart J 2007; 48: 553-567.
Togni M, Raber L, Cocchia R et al. Local vascular dysfunction after coronary paclitaxel-eluting stent implantation. Int J Cardiol 2007; 120: 212-220.
Hamilos MI, Ostojic M, Beleslin B et al., on behalf of the NOBORI Investigators. Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion. J Am Coll Cardiol 2008; 51: 2123-2129.
Yasue H, Nakagawa H, Itoh T et al. Coronary artery spasm-clinical features, diagnosis, pathogenesis, and treatment. J Cardiol 2008; 51: 2-517.
Sueda S, Ochi N, Kawada H et al. Frequency of provoked coronary vasospasm in patients undergoing coronary angiography with spasm provocation test of acetylcholine. Am J Cardiol 1999; 83: 1186-1190.
Ito S, Nakasuka K, Morimoto K et al. Angiographic and clinical characteristics of patients with acetylcholine-induced coronary vasospasm on follow-up coronary angiography following drug-eluting stent implantation. J Invas Cardiol 2011; 23: 57-64.