2009, Número 588
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Rev Med Cos Cen 2009; 66 (588)
Inhibidores de acetilcolinesterasa en el tratamiento de la enfermedad de Alzheimer
Jiménez PV
Idioma: Español
Referencias bibliográficas: 20
Paginas: 203-206
Archivo PDF: 336.41 Kb.
RESUMEN
La enfermedad de Alzheimer es la forma más común de demencia. Es una enfermedad progresivamente debilitante caracterizada por daño en la memoria y deterioro funcional que es atribuido principalmente a deficiencias colinérgicas. Su larga duración,la carga de los cuidadores y los costos asociados con la atención proporcionada contribuyen a hacer de la demencia un mayor problema de salud pública. Los inhibidores de Acetilcolinesterasa: tacrina, rivastigmina, donepezilo, galantamina y memantina, son actualmente el mejor tratamiento establecido para esta devastante enfermedad.
Conclusión: Aunque estas drogas no son la cura pueden retrasar el progreso del deterioro mental, reducir los síntomas neuropsiquiatricos y por lo tanto, representar un enfoque terapéutico racional para el tratamiento de la enfermedad de Alzheimer.
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