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Colegio de Medicos y Cirujanos República de Costa Rica

2010, Número 591

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Rev Med Cos Cen 2010; 67 (591)


Uso de antagonistas de receptores de angiotensina para el tratamiento de la prehipertension

Bolaños RH

Idioma: Español
Referencias bibliográficas: 20
Paginas: 77-80
Archivo PDF: 233.46 Kb.


RESUMEN

La prehipertensión es considerada un precursor del estadío 1 de hipertensión arterial y un predictor de riesgo cardiovascular excesivo. Es por esto que el Ensayo para Prevenir Hipertensión(TROPHY) investigó si el tratamiento farmacológico de la prehipertensión podría prevenir o posponer el desarrollo de hipertensión estadío 1. Los pacientes del TROPHY fueron asignados de manera randomizada en dos grupos, un o con candesartan y el otro placebo. Durante un periodo de cuatro años, el estadío 1 del hipertensión se desarrollo en un tercio de los pacientes del grupo placebo. El tratamiento de prehipertensión con candesartan parece ser bien tolerado y reduce el riesgo de hipertensión durante el periodo del estudio.


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