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2003, Número 1

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Rev Mex Patol Clin Med Lab 2003; 50 (1)


Virus del papiloma humano. Actualización y presentación de un caso de carcinoma esofágico asociado a VPH

Mandado PS, Haedo QW, Gra OB, Domínguez ÁC, Lazo VS, Elvírez GÁ

Idioma: Español
Referencias bibliográficas: 76
Paginas: 12-19
Archivo PDF: 97.41 Kb.


RESUMEN

Se hizo una amplia revisión bibliográfica en relación a los virus del papiloma humano (VPH) a propósito de la presencia de imágenes coilocíticas en extendidos citológicos de cánceres de esófago. En nuestro caso se realizó citología por cepillado y biopsia a un paciente con epigastralgia y disfagia marcada a los sólidos; endoscópicamente se diagnosticó esofagitis grado IV con ulceraciones y pseudopólipos en la unión esofago-gástrica. El extendido citológico mostró abundantes células típicas del VPH (coilocitos) con núcleos malignos. La enfermedad evolucionó violentamente y en las últimas endoscopias la tumoración ocluía la luz esofágica, pero las biopsias no eran concluyentes de malignidad. El paciente fue operado y el estudio histopatológico de la pieza quirúrgica demostró carcinoma epidermoide bien diferenciado de esófago, de aspecto verrucoso de baja malignidad por VPH.


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