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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2002, Número 3

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Alerg Asma Inmunol Pediatr 2002; 11 (3)


Características bioquímicas y moleculares de alergenos del látex de Hevea brasiliensis

Reyes LCAS, Rodríguez RA

Idioma: Español
Referencias bibliográficas: 65
Paginas: 92-100
Archivo PDF: 331.03 Kb.


RESUMEN

En los últimos años las reacciones de hipersensibilidad de tipo I, ocasionadas por algunas proteínas del látex de Hevea brasiliensis (hule), se han incrementado de forma importante hasta llegar a ser un problema de salud pública ocupacional en muchos países. Esto ha generado un interés especial por entender las bases moleculares e inmunológicas del reconocimiento de estos alergenos por las IgE’s de personas alérgicas a este material. Recientemente se han realizado una gran cantidad de estudios moleculares e inmunológicos sobre los alergenos del látex, lo que ha permitido que once proteínas del hule sean consideradas como las principales que participan en la sensibilización de las personas y se les ha asignado una nomenclatura oficial. Estos estudios sentarán las bases para el desarrollo de mejores métodos de diagnóstico y proveerán de nuevas herramientas para emplearse en procesos de inmunoterapia.


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