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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2009, Número 2

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Alerg Asma Inmunol Pediatr 2009; 18 (2)


Efectos inmunomoduladores de la célula cebada

Morfín MBM, Castillo MBM

Idioma: Español
Referencias bibliográficas: 24
Paginas: 47-51
Archivo PDF: 96.99 Kb.


RESUMEN

Las células cebadas tienen funciones efectoras tanto en la respuesta inmune innata, como en la adaptativa, promoviendo la inflamación alérgica, remodelación tisular y el daño a los tejidos principalmente debido a su activación sostenida. Sin embargo, los mastocitos también tienen efectos antiinflamatorios e inmunosupresores. De hecho, la célula cebada puede tanto aumentar, como suprimir algunas facetas de una misma respuesta inmunológica. La respuesta que ejercerá la célula cebada dependerá de las bases biológicas individuales.


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