Marín G, Rangel A, González-Llaven J

Idioma: Español
Referencias bibliográficas: 14
Paginas: 181-187
Archivo PDF: 104.72 Kb.

RESUMEN

The authors describe the clinical cases of a young man 22 years-old, with congenital methemoglobinemia, skin and gingival hyperpigmentation, clubbing, great effort dyspnea, discrete cardiomegalia (cardiothoracic index 0.55), 59% of hematocrit, decreasing functional hemoglobin and therefore, oxyhemoglobin decreasing, but normal arterial oxygen partial pressure and saturation. The authors discuss the oxygen transport and uptake, as well the problems induced by decreasing functional hemoglobin, pointing out the differences between the well know physiological response to hypoxemia and the sparse response to methemoglobinemia (57%), similar to the lack of monoxide intoxication response. The authors speculate that this poor response is because lack of adaptive physiological mechanisms during vertebrates evolution.

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