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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2009, Número 2

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Rev Mex Oftalmol 2009; 83 (2)


Síndrome de pseudoexfoliación. Revisión bibliográfica

Urrutia-Breton IP

Idioma: Español
Referencias bibliográficas: 62
Paginas: 57-66
Archivo PDF: 209.71 Kb.


RESUMEN

El síndrome de pseudoexfoliación es un desorden sistémico de la matriz extracelular relacionado con la edad, que no sólo causa glaucoma crónico de ángulo abierto y catarata, sino que también se relaciona con complicaciones intraoculares espontáneas y quirúrgicas. Las investigaciones recientes han permitido entender sus efectos en tejidos oculares al mejorar los criterios diagnósticos, aplicar nuevos tratamientos y desarrollar nuevas estrategias preventivas para disminuir las complicaciones quirúrgicas, así como evidenciar las asociaciones sistémicas como la morbilidad cardiovascular y cerebrovascular. Los nuevos conceptos de patología genética describen al síndrome de pseudoexfoliación como una microfibrilopatía que involucra al factor de crecimiento B-1, el estrés oxidativo, y el daño a los mecanismos de protección celular.


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